日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Common Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Epitopes Mediate Multiple Routes for Internalization and Function

常见前蛋白转化酶枯草溶菌素/Kexin 9 型 (PCSK9) 表位介导内化和功能的多种途径

Rachel M DeVay, Lynn Yamamoto, David L Shelton, Hong Liang

Characterization of proprotein convertase subtilisin/kexin type 9 (PCSK9) trafficking reveals a novel lysosomal targeting mechanism via amyloid precursor-like protein 2 (APLP2)

对前蛋白转化酶枯草溶菌素/kexin 9 型 (PCSK9) 运输的表征揭示了一种通过淀粉样蛋白前体样蛋白 2 (APLP2) 的新型溶酶体靶向机制

Rachel M DeVay, David L Shelton, Hong Liang

Increasing serum half-life and extending cholesterol lowering in vivo by engineering antibody with pH-sensitive binding to PCSK9

通过设计与 PCSK9 具有 pH 敏感结合的抗体来增加血清半衰期并延长体内降低胆固醇的时间

Javier Chaparro-Riggers, Hong Liang, Rachel M DeVay, Lanfang Bai, Janette E Sutton, Wei Chen, Tao Geng, Kevin Lindquist, Meritxell Galindo Casas, Leila M Boustany, Colleen L Brown, Jeffrey Chabot, Bruce Gomes, Pamela Garzone, Andrea Rossi, Pavel Strop, Dave Shelton, Jaume Pons, Arvind Rajpal

A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria

以线粒体为中心的遗传相互作用图揭示了线粒体内膜组织所需的支架状复合物

Suzanne Hoppins, Sean R Collins, Ann Cassidy-Stone, Eric Hummel, Rachel M Devay, Laura L Lackner, Benedikt Westermann, Maya Schuldiner, Jonathan S Weissman, Jodi Nunnari