日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A Multivalent Peptoid Conjugate Modulates Androgen Receptor Transcriptional Activity to Inhibit Therapy-resistant Prostate Cancer

多价肽缀合物通过调节雄激素受体转录活性抑制耐药性前列腺癌

Justine Habault ,Jeffrey A Schneider ,Susan Ha ,Rachel Ruoff ,Luiza D Pereira ,Joseph Puccini ,Michela Ranieri ,Ruveyda Ayasun ,Jiehui Deng ,Amanda C Kasper ,Dafna Bar-Sagi ,Kwok-Kin Wong ,Amina Zoubeidi ,Frank Claessens ,David R Wise ,Susan K Logan ,Kent Kirshenbaum ,Michael J Garabedian

MED19 encodes two unique protein isoforms that confer prostate cancer growth under low androgen through distinct gene expression programs

MED19 编码两种独特的蛋白质亚型,通过不同的基因表达程序在低雄激素条件下促进前列腺癌生长

Rachel Ruoff, Hannah Weber, Ying Wang, Hongying Huang, Ellen Shapiro, David Fenyö, Michael J Garabedian

Transcriptional regulation of Acsl1 by CHREBP and NF-kappa B in macrophages during hyperglycemia and inflammation

高血糖和炎症期间巨噬细胞中 CHREBP 和 NF-κB 对 Acsl1 的转录调控

Prashanth Thevkar-Nagesh, Justine Habault, Maud Voisin, Sophie E Ruff, Susan Ha, Rachel Ruoff, Xi Chen, Shruti Rawal, Tarik Zahr, Gyongyi Szabo, Inez Rogatsky, Edward A Fisher, Michael J Garabedian

Inhibiting LXRα phosphorylation in hematopoietic cells reduces inflammation and attenuates atherosclerosis and obesity in mice

抑制造血细胞中LXRα的磷酸化可减轻炎症,并缓解小鼠的动脉粥样硬化和肥胖。

Maud Voisin ,Elina Shrestha ,Claire Rollet ,Cyrus A Nikain ,Tatjana Josefs ,Mélanie Mahé ,Tessa J Barrett ,Hye Rim Chang ,Rachel Ruoff ,Jeffrey A Schneider ,Michela L Garabedian ,Chris Zoumadakis ,Chi Yun ,Bara Badwan ,Emily J Brown ,Adam C Mar ,Robert J Schneider ,Ira J Goldberg ,Inés Pineda-Torra ,Edward A Fisher ,Michael J Garabedian

MED19 alters AR occupancy and gene expression in prostate cancer cells, driving MAOA expression and growth under low androgen

MED19 改变前列腺癌细胞中的 AR 占有率和基因表达,在低雄激素条件下驱动 MAOA 表达和生长

Hannah Weber, Rachel Ruoff, Michael J Garabedian

Phosphoproteomics of Fibroblast Growth Factor 1 (FGF1) Signaling in Chondrocytes: Identifying the Signature of Inhibitory Response

软骨细胞中成纤维细胞生长因子 1 (FGF1) 信号传导的磷酸化蛋白质组学:识别抑制反应的特征

Jessica R Chapman, Olga Katsara, Rachel Ruoff, David Morgenstern, Shruti Nayak, Claudio Basilico, Beatrix Ueberheide, Victoria Kolupaeva

Cell type-specific control of protein synthesis and proliferation by FGF-dependent signaling to the translation repressor 4E-BP

通过 FGF 依赖的信号传导至翻译抑制因子 4E-BP,实现细胞类型特异性控制蛋白质合成和增殖

Rachel Ruoff, Olga Katsara, Victoria Kolupaeva

Regulation of androgen receptor-mediated transcription by RPB5 binding protein URI/RMP

RPB5 结合蛋白 URI/RMP 对雄激素受体介导的转录的调节

Paolo Mita, Jeffrey N Savas, Nabil Djouder, John R Yates 3rd, Susan Ha, Rachel Ruoff, Eric D Schafler, Jerome C Nwachukwu, Naoko Tanese, Nicholas J Cowan, Jiri Zavadil, Michael J Garabedian, Susan K Logan

Sin3B expression is required for cellular senescence and is up-regulated upon oncogenic stress

Sin3B 表达是细胞衰老所必需的,并在致癌应激时上调

Kathryn B Grandinetti, Petar Jelinic, Teresa DiMauro, Jessica Pellegrino, Rubén Fernández Rodríguez, Patricia M Finnerty, Rachel Ruoff, Nabeel Bardeesy, Susan K Logan, Gregory David