日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Machine learning-optimized targeted detection of alternative splicing

机器学习优化的选择性剪接靶向检测

Yang, Kevin; Islas, Nathaniel; Jewell, San; Wu, Di; Jha, Anupama; Radens, Caleb M; Pleiss, Jeffrey A; Lynch, Kristen W; Barash, Yoseph; Choi, Peter S

An Alternatively Spliced Gain-of-Function NT5C2 Isoform Contributes to Chemoresistance in Acute Lymphoblastic Leukemia

选择性剪接的获得功能 NT5C2 亚型导致急性淋巴细胞白血病产生化学耐药性

Manuel Torres-Diz, Clara Reglero, Catherine D Falkenstein, Annette Castro, Katharina E Hayer, Caleb M Radens, Mathieu Quesnel-Vallières, Zhiwei Ang, Priyanka Sehgal, Marilyn M Li, Yoseph Barash, Sarah K Tasian, Adolfo Ferrando, Andrei Thomas-Tikhonenko

RNA splicing analysis using heterogeneous and large RNA-seq datasets

利用异质性和大型RNA-seq数据集进行RNA剪接分析

Vaquero-Garcia, Jorge; Aicher, Joseph K; Jewell, San; Gazzara, Matthew R; Radens, Caleb M; Jha, Anupama; Norton, Scott S; Lahens, Nicholas F; Grant, Gregory R; Barash, Yoseph

Alternative splicing of apoptosis genes promotes human T cell survival

凋亡基因的选择性剪接促进人类T细胞存活

Davia Blake ,Caleb M Radens ,Max B Ferretti ,Matthew R Gazzara ,Kristen W Lynch

Meta-analysis of transcriptomic variation in T-cell populations reveals both variable and consistent signatures of gene expression and splicing

对T细胞群体转录组变异的荟萃分析揭示了基因表达和剪接的可变性和一致性特征

Radens, Caleb M; Blake, Davia; Jewell, Paul; Barash, Yoseph; Lynch, Kristen W

Deep profiling and custom databases improve detection of proteoforms generated by alternative splicing

深度分析和自定义数据库可提高对可变剪接产生的蛋白质形式的检测

Laura M Agosto, Matthew R Gazzara, Caleb M Radens, Simone Sidoli, Josue Baeza, Benjamin A Garcia, Kristen W Lynch

ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development

ESRP1 突变导致听力损失,这是由于选择性剪接缺陷破坏了耳蜗发育

Alex M Rohacek, Thomas W Bebee, Richard K Tilton, Caleb M Radens, Chris McDermott-Roe, Natoya Peart, Maninder Kaur, Michael Zaykaner, Benjamin Cieply, Kiran Musunuru, Yoseph Barash, John A Germiller, Ian D Krantz, Russ P Carstens, Douglas J Epstein

Transcriptome analysis of hypoxic cancer cells uncovers intron retention in EIF2B5 as a mechanism to inhibit translation

对缺氧癌细胞的转录组分析揭示了EIF2B5中内含子滞留是抑制翻译的一种机制

Brady, Lauren K; Wang, Hejia; Radens, Caleb M; Bi, Yue; Radovich, Milan; Maity, Amit; Ivan, Cristina; Ivan, Mircea; Barash, Yoseph; Koumenis, Constantinos

Phosphoproteomics reveals that glycogen synthase kinase-3 phosphorylates multiple splicing factors and is associated with alternative splicing

磷酸化蛋白质组学揭示,糖原合成酶激酶-3可磷酸化多种剪接因子,并与选择性剪接相关。

Mansi Y Shinde ,Simone Sidoli ,Katarzyna Kulej ,Michael J Mallory ,Caleb M Radens ,Amanda L Reicherter ,Rebecca L Myers ,Yoseph Barash ,Kristen W Lynch ,Benjamin A Garcia ,Peter S Klein

Recombination among GB virus C (GBV-C) isolates in the United States

美国GB病毒C(GBV-C)分离株之间的重组

Blackard, Jason T; Ma, Gang; Polen, Clarissa; DuBois, Juwen C; Gast, Jonathon; Radens, Caleb M; Sterling, Richard K; Sherman, Kenneth E