日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The eEF2 kinase coordinates the DNA damage response to cisplatin by supporting p53 activation

eEF2 激酶通过支持 p53 激活来协调对顺铂的 DNA 损伤反应

Jonathan K M Lim #, Arash Samiei #, Alberto Delaidelli, Jessica Oliveira de Santis, Vanessa Brinkmann, Christopher J Carnie, Daniel Radiloff, Laura Hruby, Alisa Kahler, Jordan Cran, Gabriel Leprivier, Poul H Sorensen

Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases

利用 CRISPR 指导的整合酶,无需双链 DNA 切割即可将大序列拖放到基因组中

Matthew T N Yarnall #,Eleonora I Ioannidi #,Cian Schmitt-Ulms #,Rohan N Krajeski #,Justin Lim,Lukas Villiger,Wenyuan Zhou,Kaiyi Jiang,Sofya K Garushyants,Nathaniel Roberts,Liyang Zhang,Christopher A Vakulskas,John A Walker 2nd,Anastasia P Kadina,Adrianna E Zepeda,Kevin Holden,Hong Ma,Jun Xie,Guangping Gao,Lander Foquet,Greg Bial,Sara K Donnelly,Yoshinari Miyata,Daniel R Radiloff,Jordana M Henderson,Andrew Ujita,Omar O Abudayyeh,Jonathan S Gootenberg

Hepatocyte-targeted siTAZ therapy lowers liver fibrosis in NASH diet-fed chimeric mice with hepatocyte-humanized livers

以肝细胞为靶点的 siTAZ 疗法可降低以肝细胞人源化肝脏为食的 NASH 嵌合小鼠的肝纤维化

Xiaobo Wang, Mary P Moore, Hongxue Shi, Yoshinari Miyata, Sara K Donnelly, Daniel R Radiloff, Ira Tabas

Characterization and Prevention of Hypovitaminosis C in Chimeric Mice with Humanized Livers

人源化肝脏嵌合小鼠维生素C缺乏症的特征及预防

Touchette, Erin K; Bates, Maria C; Johnson, Mitch C; O'Brien, Tracy C; Melton, Roger J; Long, Kelly R; Kakuni, Masakazu; Baginski, Matthew; Radiloff, Daniel R; Sagartz, John E

Oncogene-Induced Replication Stress Drives Genome Instability and Tumorigenesis

癌基因诱导的复制压力驱动基因组不稳定和肿瘤发生

Radiloff, Daniel R; Wakeman, Timothy P; Feng, Junjie; Schilling, Stephen; Seto, Edward; Wang, Xiao-Fan; Sarni, Dan; Kerem, Batsheva

Automated measurement of blood flow velocity and direction and hemoglobin oxygen saturation in the rat lung using intravital microscopy

利用活体显微镜自动测量大鼠肺内血流速度、方向和血红蛋白氧饱和度

Hanna, Gabi; Fontanella, Andrew; Palmer, Gregory; Shan, Siqing; Radiloff, Daniel R; Zhao, Yulin; Irwin, David; Hamilton, Karyn; Boico, Alina; Piantadosi, Claude A; Blueschke, Gert; Dewhirst, Mark; McMahon, Timothy; Schroeder, Thies

NDRG4 is required for cell cycle progression and survival in glioblastoma cells

NDRG4 是胶质母细胞瘤细胞周期进程和存活所必需的

Stephen H Schilling, Anita B Hjelmeland, Daniel R Radiloff, Irwin M Liu, Timothy P Wakeman, Jeffrey R Fielhauer, Erika H Foster, Justin D Lathia, Jeremy N Rich, Xiao-Fan Wang, Michael B Datto

Extracellular matrix protein betaig-h3/TGFBI promotes metastasis of colon cancer by enhancing cell extravasation

细胞外基质蛋白β-h3/TGFBI通过增强细胞外渗促进结肠癌转移

Chaoyu Ma, Yu Rong, Daniel R Radiloff, Michael B Datto, Barbara Centeno, Shideng Bao, Anthony Wai Ming Cheng, Fumin Lin, Shibo Jiang, Timothy J Yeatman, Xiao-Fan Wang

Modeling cancer patient populations in mice: complex genetic and environmental factors

在小鼠中构建癌症患者群体模型:复杂的遗传和环境因素

Radiloff, Daniel R; Rinella, Erica S; Threadgill, David W