日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Inflammasome Is Activated in the Liver of Cholestatic Patients and Aggravates Hepatic Injury in Bile Duct-Ligated Mouse

胆汁淤积患者肝脏炎症小体激活加重胆管结扎小鼠肝损伤

期刊:Cellular and Molecular Gastroenterology and Hepatology
影响因子:7.1
doi:10.1016/j.jcmgh.2019.12.008
Shi-Ying Cai, Maoxu Ge, Albert Mennone, Rafaz Hoque, Xinshou Ouyang, James L Boyer
代谢
信号转导
肝损伤
WB
炎性小体
Mouse
发表日期：2020
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Ammonia-Induced Brain Edema Requires Macrophage and T Cell Expression of Toll-Like Receptor 9

氨诱导的脑水肿需要巨噬细胞和 T 细胞表达 Toll 样受体 9

期刊:Cellular and Molecular Gastroenterology and Hepatology
影响因子:7.1
doi:10.1016/j.jcmgh.2019.08.002
Godhev Kumar Manakkat Vijay, Changyun Hu, Jian Peng, Irma Garcia-Martinez, Rafaz Hoque, Rejina Mariam Verghis, Yun Ma, Wajahat Zafar Mehal, Debbie Lindsay Shawcross, Li Wen
免疫
细胞生物学
巨噬细胞
Toll-Like Receptor
发表日期：2019
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Digoxin Suppresses Pyruvate Kinase M2-Promoted HIF-1α Transactivation in Steatohepatitis

地高辛抑制脂肪性肝炎中丙酮酸激酶 M2 促进的 HIF-1α 转录激活

期刊:Cell Metabolism
影响因子:27.7
doi:10.1016/j.cmet.2018.01.007
Xinshou Ouyang, Sheng-Na Han, Ji-Yuan Zhang, Evangelos Dioletis, Balazs Tamas Nemeth, Pal Pacher, Dechun Feng, Ramon Bataller, Joaquin Cabezas, Peter Stärkel, Joan Caballeria, Rebecca LePine Pongratz, Shi-Ying Cai, Bernd Schnabl, Rafaz Hoque, Yonglin Chen, Wei-Hong Yang, Irma Garcia-Martinez, Fu-She
代谢
免疫
肝炎
发表日期：2018
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β-Hydroxybutyrate protects from alcohol-induced liver injury via a Hcar2-cAMP dependent pathway

β-羟基丁酸通过 Hcar2-cAMP 依赖性途径预防酒精引起的肝损伤

期刊:Journal of Hepatology
影响因子:26.8
doi:10.1016/j.jhep.2018.04.004
Yonglin Chen, Xinshou Ouyang, Rafaz Hoque, Irma Garcia-Martinez, Muhammad Nadeem Yousaf, Sarah Tonack, Stefan Offermanns, Laurent Dubuquoy, Alexandre Louvet, Philippe Mathurin, Veronica Massey, Bernd Schnabl, Ramon Alberola Bataller, Wajahat Zafar Mehal
信号转导
肝损伤
GPCR/Calcium/cAMP
发表日期：2018
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Hepatocyte mitochondrial DNA drives nonalcoholic steatohepatitis by activation of TLR9

肝细胞线粒体DNA通过激活TLR9驱动非酒精性脂肪性肝炎。

期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI83885
Garcia-Martinez, Irma; Santoro, Nicola; Chen, Yonglin; Hoque, Rafaz; Ouyang, Xinshou; Caprio, Sonia; Shlomchik, Mark J; Coffman, Robert Lee; Candia, Albert; Mehal, Wajahat Zafar
TLR9
细胞生物学
线粒体
肝炎
发表日期：2016
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Activation of N-methyl-d-aspartate receptor downregulates inflammasome activity and liver inflammation via a β-arrestin-2 pathway

N-甲基-d-天冬氨酸受体的激活通过 β-arrestin-2 通路下调炎症小体活性和肝脏炎症

期刊:American Journal of Physiology-Gastrointestinal and Liver Physiology
影响因子:3.9
doi:10.1152/ajpgi.00073.2014
Ahmad Farooq, Rafaz Hoque, Xinshou Ouyang, Ahsan Farooq, Ayaz Ghani, Kaimul Ahsan, Mateus Guerra, Wajahat Zafar Mehal
信号转导
Immunology/Inflammation
炎性小体
发表日期：2014
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Therapeutic strategies in inflammasome mediated diseases of the liver

肝脏炎症小体介导疾病的治疗策略

期刊:Journal of Hepatology
影响因子:33
doi:10.1016/j.jhep.2012.12.017
Hoque, Rafaz; Vodovotz, Yoram; Mehal, Wajahat
炎症
炎性小体
炎症/感染
肝炎
炎性小体
免疫/内分泌
发表日期：2013
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A novel small-molecule enantiomeric analogue of traditional (-)-morphinans has specific TLR9 antagonist properties and reduces sterile inflammation-induced organ damage

传统 (-)-吗啡喃的新型小分子对映体类似物具有特定的 TLR9 拮抗剂特性，可减少无菌性炎症引起的器官损伤

期刊:Journal of Immunology
影响因子:3.6
doi:10.4049/jimmunol.1202184
Rafaz Hoque, Ahmad Farooq, Ahsan Malik, Bobby N Trawick, David W Berberich, Joseph P McClurg, Karen P Galen, Wajahat Mehal
免疫
Immunology/Inflammation
发表日期：2013
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P2X7 receptor-mediated purinergic signaling promotes liver injury in acetaminophen hepatotoxicity in mice

P2X7 受体介导的嘌呤能信号促进小鼠对乙酰氨基酚肝毒性中的肝损伤

期刊:American Journal of Physiology-Gastrointestinal and Liver Physiology
影响因子:3.9
doi:10.1152/ajpgi.00352.2011
Rafaz Hoque, Muhammed Adnan Sohail, Steven Salhanick, Ahsan F Malik, Ayaz Ghani, Simon C Robson, Wajahat Z Mehal
代谢
信号转导
肝损伤
发表日期：2012
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Sterile inflammatory response in acute pancreatitis

急性胰腺炎中的无菌性炎症反应

期刊:Pancreas
影响因子:1.7
doi:10.1097/MPA.0b013e3182321500
Hoque, Rafaz; Malik, Ahsan F; Gorelick, Fred; Mehal, Wajahat Z
胰腺炎
炎症/感染
炎症
发表日期：2012
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