Raghida相关文献与解析，生知库 | 链接生命科学的每一步

van Ravensteijn, Bas G P; Corona, Patrick T; Datta, Anukta; Dai, Kexin; Bou Zerdan, Raghida; Weigandt, Katie M; Murphy, Ryan P; Hawker, Craig J; Helgeson, Matthew E

发表日期：2026

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XMT-2056, a HER2-Directed STING Agonist Antibody-Drug Conjugate, Induces Innate Antitumor Immune Responses by Acting on Cancer Cells and Tumor-Resident Immune Cells.

XMT-2056 是一种 HER2 靶向 STING 激动剂抗体药物偶联物，通过作用于癌细胞和肿瘤驻留免疫细胞来诱导先天性抗肿瘤免疫反应

期刊:Clinical Cancer Research

影响因子:10.2

doi:10.1158/1078-0432.CCR-24-2449

Bukhalid Raghida A, Duvall Jeremy R, Lancaster Kelly, Catcott Kalli C, Malli Cetinbas Naniye, Monnell Travis, Routhier Caitlin, Thomas Joshua D, Bentley Keith W, Collins Scott D, Ditty Elizabeth, Eitas Timothy K, Kelleher Eugene W, Shaw Pamela, Soomer-James Jahna, Ter-Ovanesyan Elena, Xu Ling, Zurita Jeffrey, Toader Dorin, Damelin Marc, Lowinger Timothy B

The Novel Imiqualine EAPB02303 Is a Potent Drug for Treating Acute Myeloid Leukemia.

新型咪喹啉 EAPB02303 是一种治疗急性髓系白血病的强效药物

期刊:Biomolecules

影响因子:4.8

doi:10.3390/biom15050741

Makhoul Perla, Hleihel Rita, Itani Shaymaa, Hamie Maguy, Pagniagua-Gayraud Stephanie, Patinote Cindy, Richaud Myriam, Merhi Raghida Abou, El-Sabban Marwan, Galas Simon, Deleuze-Masquefa Carine, Bonnet Pierre-Antoine, El Hajj Hiba

Refractory severe aplastic anemia in a child: treatment failure and access barriers in a low-resource setting

儿童难治性重型再生障碍性贫血：资源匮乏环境下的治疗失败和就医障碍

期刊:Annals of Medicine and Surgery

影响因子:1.6

doi:10.1097/MS9.0000000000004007

Karaki, Zeinab; Chemaly, Chrystelle; Kotaich, Jana; Shmeis, Ali; Dhayni, Raghida

Unusual diagnosis in a Lebanese child with persistent hyper eosinophilia: a case report

黎巴嫩一名持续性嗜酸性粒细胞增多症患儿的罕见诊断：病例报告

期刊:Annals of Medicine and Surgery

影响因子:1.6

doi:10.1097/MS9.0000000000003240

Abbass, Mortada; Joudi, Lana; Khalifeh, Haidar; Almasri, Hussein; Dhayni, Raghida

Tumor cell-directed STING agonist antibody-drug conjugates induce type III interferons and anti-tumor innate immune responses

靶向肿瘤细胞的STING激动剂抗体药物偶联物可诱导III型干扰素和抗肿瘤先天免疫反应。

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-024-49932-4

Naniye Malli Cetinbas ，Travis Monnell ，Jahna Soomer-James ，Pamela Shaw ，Kelly Lancaster ，Kalli C Catcott ，Melissa Dolan ，Rebecca Mosher ，Caitlin Routhier ，Chen-Ni Chin ，Dorin Toader ，Jeremy Duvall ，Raghida Bukhalid ，Timothy B Lowinger ，Marc Damelin

Discovery and Optimization of a STING Agonist Platform for Application in Antibody Drug Conjugates

发现并优化 STING 激动剂平台以应用于抗体药物偶联物

期刊:Journal of Medicinal Chemistry

影响因子:6.8

doi:10.1021/acs.jmedchem.3c00907

Jeremy R Duvall, Joshua D Thomas, Raghida A Bukhalid, Kalli C Catcott, Keith W Bentley, Scott D Collins, Timothy Eitas, Brian D Jones, Eugene W Kelleher, Kelly Lancaster, Marina Protopopova, Soumya S Ray, Elena Ter-Ovanesyan, Ling Xu, Liping Yang, Jeffrey Zurita, Marc Damelin, Dorin Toader, Timothy

STING

发表日期：2023

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The nucleolar protein GNL3 prevents resection of stalled replication forks

核仁蛋白GNL3可阻止停滞复制叉的切除。

期刊:EMBO Reports

影响因子:6.5

doi:10.15252/embr.202357585

Rana Lebdy ,Marine Canut ,Julie Patouillard ,Jean-Charles Cadoret ,Anne Letessier ,Josiane Ammar ,Jihane Basbous ,Serge Urbach ,Benoit Miotto ,Angelos Constantinou ,Raghida Abou Merhi ,Cyril Ribeyre

GNL3

发表日期：2023

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The organizer of chromatin topology RIF1 ensures cellular resilience to DNA replication stress

染色质拓扑结构的组织者RIF1确保细胞对DNA复制压力的抵抗力。

期刊:Life Science Alliance

影响因子:3.3

doi:10.26508/lsa.202101186

Rana Lebdy ,Julie Patouillard ,Marion Larroque ,Serge Urbach ,Raghida Abou Merhi ,Christian Larroque ,Cyril Ribeyre

Rbp95 binds to 25S rRNA helix H95 and cooperates with the Npa1 complex during early pre-60S particle maturation

Rbp95 与 25S rRNA 螺旋 H95 结合，并在 60S 前粒子成熟早期与 Npa1 复合物协同作用

期刊:Nucleic Acids Research

影响因子:16.6

doi:10.1093/nar/gkac724

Priya Bhutada, Sébastien Favre, Mariam Jaafar, Jutta Hafner, Laura Liesinger, Stefan Unterweger, Karin Bischof, Barbara Darnhofer, Devanarayanan Siva Sankar, Gerald Rechberger, Raghida Abou Merhi, Simon Lebaron, Ruth Birner-Gruenberger, Dieter Kressler, Anthony K Henras, Brigitte Pertschy

发表日期：2022

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Topology-Dependent Polymer Stretching and Scission in Solution at Extreme Shear Rates

极端剪切速率下溶液中拓扑结构依赖性聚合物拉伸和断裂

XMT-2056, a HER2-Directed STING Agonist Antibody-Drug Conjugate, Induces Innate Antitumor Immune Responses by Acting on Cancer Cells and Tumor-Resident Immune Cells.

XMT-2056 是一种 HER2 靶向 STING 激动剂抗体药物偶联物，通过作用于癌细胞和肿瘤驻留免疫细胞来诱导先天性抗肿瘤免疫反应

The Novel Imiqualine EAPB02303 Is a Potent Drug for Treating Acute Myeloid Leukemia.

新型咪喹啉 EAPB02303 是一种治疗急性髓系白血病的强效药物

Refractory severe aplastic anemia in a child: treatment failure and access barriers in a low-resource setting

儿童难治性重型再生障碍性贫血：资源匮乏环境下的治疗失败和就医障碍

Unusual diagnosis in a Lebanese child with persistent hyper eosinophilia: a case report

黎巴嫩一名持续性嗜酸性粒细胞增多症患儿的罕见诊断：病例报告

Tumor cell-directed STING agonist antibody-drug conjugates induce type III interferons and anti-tumor innate immune responses

靶向肿瘤细胞的STING激动剂抗体药物偶联物可诱导III型干扰素和抗肿瘤先天免疫反应。

Discovery and Optimization of a STING Agonist Platform for Application in Antibody Drug Conjugates

发现并优化 STING 激动剂平台以应用于抗体药物偶联物

The nucleolar protein GNL3 prevents resection of stalled replication forks

核仁蛋白GNL3可阻止停滞复制叉的切除。

The organizer of chromatin topology RIF1 ensures cellular resilience to DNA replication stress

染色质拓扑结构的组织者RIF1确保细胞对DNA复制压力的抵抗力。

Rbp95 binds to 25S rRNA helix H95 and cooperates with the Npa1 complex during early pre-60S particle maturation

Rbp95 与 25S rRNA 螺旋 H95 结合，并在 60S 前粒子成熟早期与 Npa1 复合物协同作用