IFN-alpha and bortezomib overcome Bcl-2 and Mcl-1 overexpression in melanoma cells by stimulating the extrinsic pathway of apoptosis
IFN-α和硼替佐米通过刺激细胞凋亡的外源性途径,克服黑色素瘤细胞中Bcl-2和Mcl-1的过度表达。
期刊:Cancer Research
影响因子:16.6
doi:10.1158/0008-5472.CAN-08-0426
Lesinski, Gregory B; Raig, Ene T; Guenterberg, Kristan; Brown, Lloyd; Go, Michael R; Shah, Nisha N; Lewis, Adrian; Quimper, Megan; Hade, Erinn; Young, Gregory; Chaudhury, Abhik Ray; Ladner, Katherine J; Guttridge, Denis C; Bouchard, Page; Carson, William E 3rd
Bcl-2
黑色素瘤
凋亡
表观遗传
IFN-α
细胞生物学