日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Natural Product Target Identification of Wheldone, a Fungal Metabolite, as a KIF11 Inhibitor in Ovarian Cancer Using the DiffPOP (Differential Protein Precipitation) Method

利用DiffPOP(差异蛋白沉淀)法鉴定真菌代谢产物Wheldone作为卵巢癌中KIF11抑制剂的天然产物靶点

Khin, Manead; Saldana, Alejandra Cavazos; Rangel-Grimaldo, Manuel; Raja, Huzefa A; Abegg, Daniel; Ekiert, Julia; Liu, Chang; Misra, Sweta; Ratia, Kiira; Adibekian, Alexander; Gao, Yu; Kulp, Samuel K; Coss, Christopher C; Oberlies, Nicholas H; Burdette, Joanna E

Scaling up the production of fungal perylenequinones and investigating their biosynthesis through stable isotope labeling

扩大真菌苝醌的生产规模,并通过稳定同位素标记研究其生物合成

Al-Qiam, Reema A; Dumbare, Sachin; Graf, Tyler N; Vidar, Warren S; Raja, Huzefa A; Pearce, Cedric J; Hematian, Shabnam; Oberlies, Nicholas H

Redox Homeostasis as a Key Regulator of Intramolecular Cyclization in Fungal Perylenequinones

氧化还原稳态是真菌苝醌分子内环化反应的关键调节因子

Al-Qiam, Reema A; Khan, Firoz S T; Raja, Huzefa A; Graf, Tyler N; Pearce, Cedric J; Oberlies, Nicholas H; Hematian, Shabnam

Beyond Monomers: Discovery of Bioactive Naphthoquinone Heterodimers and Perenniporides from Pyrenochaetopsis Species

超越单体:从 Pyrenochaetopsis 物种中发现具有生物活性的萘醌异二聚体和 Perenniporides

Al-Qiam, Reema A; Rangel-Grimaldo, Manuel; Chauvin, Isabel M; Kaweesa, Elizabeth N; Khin, Manead; Raja, Huzefa A; Orjala, Jimmy; Burdette, Joanna E; Pearce, Cedric J; Oberlies, Nicholas H

Studies on the epipolythiodioxopiperazine alkaloid verticillin D: Scaled production, streamlined purification, and absolute configuration

关于表多硫代二氧哌嗪生物碱维替西林D的研究:规模化生产、简化纯化和绝对构型

Pierre, Herma C; Patel, Devyani J; Raja, Huzefa A; Darveaux, Blaise A; Patel, Krupa I; Mardiana, Lina; Longcake, Alexandra; Hall, Michael J; Probert, Michael R; Pearce, Cedric J; Oberlies, Nicholas H

An integrative genomic and chemical similarity approach linking fungal secondary metabolites and biosynthetic gene clusters

一种整合基因组学和化学相似性的方法,将真菌次生代谢产物和生物合成基因簇联系起来

Steffen, Karin; Rangel-Grimaldo, Manuel; Sauters, Thomas J C; Rinker, David C; Raja, Huzefa A; Graf, Tyler N; Gumilang, Adiyantara; Riedling, Olivia L; Goldman, Gustavo H; Oberlies, Nicholas H; Rokas, Antonis

Verticillins: fungal epipolythiodioxopiperazine alkaloids with chemotherapeutic potential

维替西林:具有化学治疗潜力的真菌表多硫代二氧哌嗪生物碱

Pierre, Herma C; Amrine, Chiraz Soumia M; Doyle, Michael G; Salvi, Amrita; Raja, Huzefa A; Chekan, Jonathan R; Huntsman, Andrew C; Fuchs, James R; Liu, Kebin; Burdette, Joanna E; Pearce, Cedric J; Oberlies, Nicholas H

Phylogenomics reveals extensive misidentification of fungal strains from the genus Aspergillus

系统发育基因组学揭示了曲霉属真菌菌株的大量错误鉴定。

Steenwyk, Jacob L; Balamurugan, Charu; Raja, Huzefa A; Gonçalves, Carla; Li, Ningxiao; Martin, Frank; Berman, Judith; Oberlies, Nicholas H; Gibbons, John G; Goldman, Gustavo H; Geiser, David M; Houbraken, Jos; Hibbett, David S; Rokas, Antonis

Trachymyrmex septentrionalis ants promote fungus garden hygiene using Trichoderma-derived metabolite cues

北方切叶蚁利用木霉衍生的代谢物信号促进真菌花园的卫生。

Kyle, Kathleen E; Puckett, Sara P; Caraballo-Rodríguez, Andrés Mauricio; Rivera-Chávez, José; Samples, Robert M; Earp, Cody E; Raja, Huzefa A; Pearce, Cedric J; Ernst, Madeleine; van der Hooft, Justin J J; Adams, Madison E; Oberlies, Nicholas H; Dorrestein, Pieter C; Klassen, Jonathan L; Balunas, Marcy J

Embellicines C-E: Macrocyclic Alkaloids with a Cyclopenta[b]fluorene Ring System from the Fungus Sarocladium sp

Embellicines CE:来自真菌Sarocladium sp.的具有环戊并[b]芴环系的环状生物碱

Al Subeh, Zeinab Y; Flores-Bocanegra, Laura; Raja, Huzefa A; Burdette, Joanna E; Pearce, Cedric J; Oberlies, Nicholas H