The SCFFBXO46 ubiquitin ligase complex mediates degradation of the tumor suppressor FBXO31 and thereby prevents premature cellular senescence
SCFFBXO46 泛素连接酶复合物介导肿瘤抑制因子 FBXO31 的降解,从而防止细胞过早衰老
期刊:Journal of Biological Chemistry
影响因子:4
doi:10.1074/jbc.RA118.005354
Srinadh Choppara, Sankaran Ganga, Rajeshkumar Manne, Parul Dutta, Shailza Singh, Manas Kumar Santra
信号转导
肿瘤
其它细胞
WB
Senescence
JNK