日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Trimethylammonium-diphenylhexatriene and propionic acid-diphenylhexatriene are sensitive fluorescence probes of amyloid formation by human IAPP

三甲基铵-二苯基己三烯和丙酸-二苯基己三烯是人胰岛淀粉样多肽(IAPP)淀粉样蛋白形成的灵敏荧光探针。

Lee, Kyung-Hoon; Manathunga, Lakshan; Li, Ming-Hao; London, Erwin; Raleigh, Daniel P

Modulation of islet amyloid polypeptide induced β-cell toxicity and amyloid formation by serum albumin proteins

血清白蛋白对胰岛淀粉样多肽诱导的β细胞毒性和淀粉样蛋白形成具有调节作用

Zhyvoloup, Alexander; Ridgway, Zachary; Prashanth, Ananya; Raleigh, Daniel P

Experimental and computational analysis of the basis for accelerated amyloid formation by a disease linked mutant of human islet amyloid polypeptide

对人类胰岛淀粉样多肽疾病相关突变体加速淀粉样蛋白形成机制的实验和计算分析

Manathunga, Lakshan; Akter, Rehana; Zou, Junjie; Simmerling, Carlos; Raleigh, Daniel P

On the plasticity of amyloid formation: The impact of destabilizing small to large substitutions on islet amyloid polypeptide amyloid formation

关于淀粉样蛋白形成的可塑性:从小到大的不稳定氨基酸替换对胰岛淀粉样多肽淀粉样蛋白形成的影响

Manathunga, Lakshan; Akter, Rehana; Zhyvoloup, Alexander; Simmerling, Carlos; Raleigh, Daniel P

Interspecies Variation Affects Islet Amyloid Polypeptide Membrane Binding

物种间差异影响胰岛淀粉样多肽膜结合

Sanders, Henry M; Chalyavi, Farzaneh; Fields, Caitlyn R; Kostelic, Marius M; Li, Ming-Hao; Raleigh, Daniel P; Zanni, Martin T; Marty, Michael T

Impact of Ca(2+) on membrane catalyzed IAPP amyloid formation and IAPP induced vesicle leakage

Ca²⁺对膜催化IAPP淀粉样蛋白形成和IAPP诱导的囊泡渗漏的影响

Li, Ming-Hao; Zhang, Xiaoxue; London, Erwin; Raleigh, Daniel P

Scaffold Hopping Transformations Using Auxiliary Restraints for Calculating Accurate Relative Binding Free Energies

利用辅助约束计算精确相对结合自由能的支架跃迁变换

Zou, Junjie; Li, Zhipeng; Liu, Shuai; Peng, Chunwang; Fang, Dong; Wan, Xiao; Lin, Zhixiong; Lee, Tai-Sung; Raleigh, Daniel P; Yang, Mingjun; Simmerling, Carlos

Preparation of Asymmetric Vesicles with Trapped CsCl Avoids Osmotic Imbalance, Non-Physiological External Solutions, and Minimizes Leakage

制备包裹氯化铯的不对称囊泡可避免渗透压失衡、非生理性外部溶液,并最大限度地减少泄漏。

Li, Ming-Hao; Raleigh, Daniel P; London, Erwin

Protein unfolded states populated at high and ambient pressure are similarly compact

在高压和常压下存在的蛋白质展开态都具有类似的紧凑性。

Harish, Balasubramanian; Gillilan, Richard E; Zou, Junjie; Wang, Jinqiu; Raleigh, Daniel P; Royer, Catherine A

The Fluorescent Dye 1,6-Diphenyl-1,3,5-hexatriene Binds to Amyloid Fibrils Formed by Human Amylin and Provides a New Probe of Amylin Amyloid Kinetics

荧光染料1,6-二苯基-1,3,5-己三烯与人胰淀素形成的淀粉样原纤维结合,为研究胰淀素淀粉样动力学提供了一种新的探针。

Li, Ming-Hao; Manathunga, Lakshan; London, Erwin; Raleigh, Daniel P