日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Author Correction: Transcriptional characterization of iPSC-derived microglia as a model for therapeutic development in neurodegeneration

作者更正:iPSC衍生小胶质细胞的转录组特征分析作为神经退行性疾病治疗开发的模型

Ramaswami, Gokul; Yuva-Aydemir, Yeliz; Akerberg, Brynn; Matthews, Bryan; Williams, Jenna; Golczer, Gabriel; Huang, Jiaqi; Al Abdullatif, Ali; Huh, Dann; Burkly, Linda C; Engle, Sandra J; Grossman, Iris; Sehgal, Alfica; Sigova, Alla A; Fremeau, Robert T Jr; Liu, Yuting; Bumcrot, David

Broad transcriptomic dysregulation occurs across the cerebral cortex in ASD

自闭症谱系障碍患者的大脑皮层存在广泛的转录组失调。

Gandal, Michael J; Haney, Jillian R; Wamsley, Brie; Yap, Chloe X; Parhami, Sepideh; Emani, Prashant S; Chang, Nathan; Chen, George T; Hoftman, Gil D; de Alba, Diego; Ramaswami, Gokul; Hartl, Christopher L; Bhattacharya, Arjun; Luo, Chongyuan; Jin, Ting; Wang, Daifeng; Kawaguchi, Riki; Quintero, Diana; Ou, Jing; Wu, Ye Emily; Parikshak, Neelroop N; Swarup, Vivek; Belgard, T Grant; Gerstein, Mark; Pasaniuc, Bogdan; Geschwind, Daniel H

Developmentally regulated alternate 3' end cleavage of nascent transcripts controls dynamic changes in protein expression in an adult stem cell lineage

发育调控的新生转录本3'末端选择性切割控制着成体干细胞谱系中蛋白质表达的动态变化

Berry, Cameron W; Olivares, Gonzalo H; Gallicchio, Lorenzo; Ramaswami, Gokul; Glavic, Alvaro; Olguín, Patricio; Li, Jin Billy; Fuller, Margaret T

Coexpression network architecture reveals the brain-wide and multiregional basis of disease susceptibility

共表达网络结构揭示了疾病易感性的全脑和多区域基础

Hartl, Christopher L; Ramaswami, Gokul; Pembroke, William G; Muller, Sandrine; Pintacuda, Greta; Saha, Ashis; Parsana, Princy; Battle, Alexis; Lage, Kasper; Geschwind, Daniel H

Alterations in Retrotransposition, Synaptic Connectivity, and Myelination Implicated by Transcriptomic Changes Following Maternal Immune Activation in Nonhuman Primates.

非人灵长类动物母体免疫激活后转录组变化所揭示的逆转录转座、突触连接和髓鞘形成的变化

Page Nicholas F, Gandal Michael J, Estes Myka L, Cameron Scott, Buth Jessie, Parhami Sepideh, Ramaswami Gokul, Murray Karl, Amaral David G, Van de Water Judy A, Schumann Cynthia M, Carter Cameron S, Bauman Melissa D, McAllister A Kimberley, Geschwind Daniel H

Gene co-expression network analysis in human spinal cord highlights mechanisms underlying amyotrophic lateral sclerosis susceptibility

人类脊髓基因共表达网络分析揭示了肌萎缩侧索硬化症易感性的潜在机制

Wang, Jerry C; Ramaswami, Gokul; Geschwind, Daniel H

Integrative genomics identifies a convergent molecular subtype that links epigenomic with transcriptomic differences in autism

整合基因组学发现了一种趋同的分子亚型,该亚型将自闭症的表观基因组差异与转录组差异联系起来。

Ramaswami, Gokul; Won, Hyejung; Gandal, Michael J; Haney, Jillian; Wang, Jerry C; Wong, Chloe C Y; Sun, Wenjie; Prabhakar, Shyam; Mill, Jonathan; Geschwind, Daniel H

Genome-wide DNA methylation profiling identifies convergent molecular signatures associated with idiopathic and syndromic autism in post-mortem human brain tissue

全基因组DNA甲基化谱分析在死后人脑组织中鉴定出与特发性和综合征性自闭症相关的趋同分子特征

Wong, Chloe C Y; Smith, Rebecca G; Hannon, Eilis; Ramaswami, Gokul; Parikshak, Neelroop N; Assary, Elham; Troakes, Claire; Poschmann, Jeremie; Schalkwyk, Leonard C; Sun, Wenjie; Prabhakar, Shyam; Geschwind, Daniel H; Mill, Jonathan

Shared Molecular Neuropathology Across Major Psychiatric Disorders Parallels Polygenic Overlap

主要精神疾病的共同分子神经病理学特征与多基因重叠现象相似

Gandal, Michael J; Haney, Jillian R; Parikshak, Neelroop N; Leppa, Virpi; Ramaswami, Gokul; Hartl, Chris; Schork, Andrew J; Appadurai, Vivek; Buil, Alfonso; Werge, Thomas M; Liu, Chunyu; White, Kevin P; Geschwind, Daniel H

Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap

主要精神疾病的共同分子神经病理学特征与多基因重叠现象相平行。

Gandal, Michael J; Haney, Jillian R; Parikshak, Neelroop N; Leppa, Virpi; Ramaswami, Gokul; Hartl, Chris; Schork, Andrew J; Appadurai, Vivek; Buil, Alfonso; Werge, Thomas M; Liu, Chunyu; White, Kevin P; Horvath, Steve; Geschwind, Daniel H