日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discovery and development of a new oxazolidinone with reduced toxicity for the treatment of tuberculosis

发现和开发一种毒性降低的新型噁唑烷酮类药物用于治疗结核病

Crowley, Brendan M; Boshoff, Helena I; Boving, Aidan; Tan, Vee Y; Zhu, Jianghai; Hoyt, Forrest; Miller, Randy R; Ehrhart, Julie; Boyce, Christopher W; Young, Katherine; Nantermet, Philippe G; Su, Jing; Yang, Lihu; Painter, Ronald E; Corcoran, Emily B; Hoar, Jason L; Oh, Sangmi; Holtzman, David L; Levi, Micha; Anderson, Aparna; Otieno, Monicah A; Zimmerman, Matthew; Kaya, Firat; Massoudi, Lisa M; Ramey, Michelle E; Bauman, Allison A; Lenaerts, Anne J; Roberston, Gregory T; Dartois, Véronique; Wells, Charles D; Barry, Clifton E 3rd; Olsen, David B

Contribution of front-line, standard-of-care drugs to bactericidal responses, resistance emergence, and cure in murine models of easy- or hard-to-treat tuberculosis disease

一线标准治疗药物对易治性或难治性结核病小鼠模型中杀菌反应、耐药性产生和治愈的贡献

Peroutka-Bigus, Nathan; Brooks, Elizabeth J; Ramey, Michelle E; D'Erasmo, Hope; Ernest, Jackie P; Bauman, Allison A; Woolhiser, Lisa K; Savic, Radojka M; Lenaerts, Anne J; Aldridge, Bree B; Sarathy, Jansy P; Robertson, Gregory T

Erratum for Peroutka-Bigus et al., "Contribution of front-line, standard-of-care drugs to bactericidal responses, resistance emergence, and cure in murine models of easy- or hard-to-treat tuberculosis disease"

更正:Peroutka-Bigus 等人,“一线标准治疗药物对易治或难治性结核病小鼠模型中杀菌反应、耐药性出现和治愈的贡献”

Peroutka-Bigus, Nathan; Brooks, Elizabeth J; Ramey, Michelle E; D'Erasmo, Hope; Ernest, Jackie P; Bauman, Allison A; Woolhiser, Lisa K; Savic, Radojka M; Lenaerts, Anne J; Aldridge, Bree B; Sarathy, Jansy P; Robertson, Gregory T

Spectinamide MBX-4888A exhibits favorable lesion and tissue distribution and promotes treatment shortening in advanced murine models of tuberculosis

Spectinamide MBX-4888A 在晚期小鼠结核病模型中表现出良好的病灶和组织分布,并能缩短治疗时间。

Bauman, Allison A; Sarathy, Jansy P; Kaya, Firat; Massoudi, Lisa M; Scherman, Michael S; Hastings, Courtney; Liu, Jiuyu; Xie, Min; Brooks, Elizabeth J; Ramey, Michelle E; Jones, Isabelle L; Benedict, Noalani D; Maclaughlin, Madelyn R; Miller-Dawson, Jake A; Waidyarachchi, Samanthi L; Butler, Michelle M; Bowlin, Terry L; Zimmerman, Matthew D; Lenaerts, Anne J; Meibohm, Bernd; Gonzalez-Juarrero, Mercedes; Lyons, Michael A; Dartois, Veronique; Lee, Richard E; Robertson, Gregory T

Drug distribution and efficacy of the DprE1 inhibitor BTZ-043 in the C3HeB/FeJ mouse tuberculosis model.

DprE1抑制剂BTZ-043在C3HeB/FeJ小鼠结核病模型中的药物分布和疗效

Ramey Michelle E, Kaya Firat, Bauman Allison A, Massoudi Lisa M, Sarathy Jansy P, Zimmerman Matthew D, Scott Dashick W L, Job Alyx M, Miller-Dawson Jake A, Podell Brendan K, Lyons Michael A, Dartois Véronique, Lenaerts Anne J, Robertson Gregory T

Combination of Mycobacterium tuberculosis RS Ratio and CFU Improves the Ability of Murine Efficacy Experiments to Distinguish between Drug Treatments

结核分枝杆菌RS比率和CFU的组合提高了小鼠疗效实验区分药物治疗的能力

Dide-Agossou, Christian; Bauman, Allison A; Ramey, Michelle E; Rossmassler, Karen; Al Mubarak, Reem; Pauly, Samantha; Voskuil, Martin I; Garcia-Cremades, Maria; Savic, Rada M; Nahid, Payam; Moore, Camille M; Tasneen, Rokeya; Nuermberger, Eric L; Robertson, Gregory T; Walter, Nicholas D

Mycobacterium tuberculosis precursor rRNA as a measure of treatment-shortening activity of drugs and regimens

结核分枝杆菌前体 rRNA 作为药物和治疗方案缩短疗程活性的指标

Walter, Nicholas D; Born, Sarah E M; Robertson, Gregory T; Reichlen, Matthew; Dide-Agossou, Christian; Ektnitphong, Victoria A; Rossmassler, Karen; Ramey, Michelle E; Bauman, Allison A; Ozols, Victor; Bearrows, Shelby C; Schoolnik, Gary; Dolganov, Gregory; Garcia, Benjamin; Musisi, Emmanuel; Worodria, William; Huang, Laurence; Davis, J Lucian; Nguyen, Nhung V; Nguyen, Hung V; Nguyen, Anh T V; Phan, Ha; Wilusz, Carol; Podell, Brendan K; Sanoussi, N' Dira; de Jong, Bouke C; Merle, Corinne S; Affolabi, Dissou; McIlleron, Helen; Garcia-Cremades, Maria; Maidji, Ekaterina; Eshun-Wilson, Franceen; Aguilar-Rodriguez, Brandon; Karthikeyan, Dhuvarakesh; Mdluli, Khisimuzi; Bansbach, Cathy; Lenaerts, Anne J; Savic, Radojka M; Nahid, Payam; Vásquez, Joshua J; Voskuil, Martin I

Digital Image Analysis of Heterogeneous Tuberculosis Pulmonary Pathology in Non-Clinical Animal Models using Deep Convolutional Neural Networks

利用深度卷积神经网络对非临床动物模型中异质性结核病肺部病理进行数字图像分析

Asay, Bryce C; Edwards, Blake Blue; Andrews, Jenna; Ramey, Michelle E; Richard, Jameson D; Podell, Brendan K; Gutiérrez, Juan F Muñoz; Frank, Chad B; Magunda, Forgivemore; Robertson, Gregory T; Lyons, Michael; Ben-Hur, Asa; Lenaerts, Anne J