日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Glyphosate exposure exacerbates neuroinflammation and Alzheimer's disease-like pathology despite a 6-month recovery period in mice

尽管小鼠经过 6 个月的恢复期,但草甘膦暴露仍会加剧神经炎症和阿尔茨海默病样病理

Samantha K Bartholomew, Wendy Winslow, Ritin Sharma, Khyatiben V Pathak, Savannah Tallino, Jessica M Judd, Hector Leon, Julie Turk, Patrick Pirrotte #, Ramon Velazquez #

Assessing the Benefit of Dietary Choline Supplementation Throughout Adulthood in the Ts65Dn Mouse Model of Down Syndrome

评估唐氏综合症 Ts65Dn 小鼠模型成年期补充膳食胆碱的益处

Savannah Tallino, Rachel Etebari, Ian McDonough, Hector Leon, Isabella Sepulveda, Wendy Winslow, Samantha K Bartholomew, Sylvia E Perez, Elliott J Mufson, Ramon Velazquez

Inflammation and the pathological progression of Alzheimer's disease are associated with low circulating choline levels

炎症和阿尔茨海默病的病理进展与循环胆碱水平低有关

Jessica M Judd, Paniz Jasbi, Wendy Winslow, Geidy E Serrano, Thomas G Beach, Judith Klein-Seetharaman, Ramon Velazquez

Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks

饮食中摄入胆碱对于预防全身器官病变和减少阿尔茨海默病的症状是必要的

Nikhil Dave, Jessica M Judd, Annika Decker, Wendy Winslow, Patrick Sarette, Oscar Villarreal Espinosa, Savannah Tallino, Samantha K Bartholomew, Alina Bilal, Jessica Sandler, Ian McDonough, Joanna K Winstone, Erik A Blackwood, Christopher Glembotski, Timothy Karr, Ramon Velazquez

Glyphosate infiltrates the brain and increases pro-inflammatory cytokine TNFα: implications for neurodegenerative disorders

草甘膦渗入大脑并增加促炎细胞因子 TNFα:对神经退行性疾病的影响

Joanna K Winstone, Khyatiben V Pathak, Wendy Winslow, Ignazio S Piras, Jennifer White, Ritin Sharma, Matthew J Huentelman, Patrick Pirrotte, Ramon Velazquez

Temporal and brain region-specific elevations of soluble Amyloid-β40-42 in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease

唐氏综合症和阿尔茨海默病的 Ts65Dn 小鼠模型中可溶性淀粉样蛋白-β40-42 在时间和大脑区域特异性升高

Savannah Tallino, Wendy Winslow, Samantha K Bartholomew, Ramon Velazquez

Identification of retinoblastoma binding protein 7 (Rbbp7) as a mediator against tau acetylation and subsequent neuronal loss in Alzheimer's disease and related tauopathies

鉴定视网膜母细胞瘤结合蛋白 7 (Rbbp7) 为抵抗阿尔茨海默病和相关 tauopathies 中的 tau 乙酰化和随后的神经元丢失的介质

Nikhil Dave, Austin S Vural, Ignazio S Piras, Wendy Winslow, Likith Surendra, Joanna K Winstone, Thomas G Beach, Matthew J Huentelman, Ramon Velazquez

IntelliCage Automated Behavioral Phenotyping Reveals Behavior Deficits in the 3xTg-AD Mouse Model of Alzheimer's Disease Associated With Brain Weight

IntelliCage 自动行为表型分析揭示了 3xTg-AD 小鼠模型中与脑重量相关的阿尔茨海默病行为缺陷

Wendy Winslow, Ian McDonough, Savannah Tallino, Annika Decker, Austin S Vural, Ramon Velazquez

Maternal choline supplementation ameliorates Alzheimer's disease pathology by reducing brain homocysteine levels across multiple generations

母体补充胆碱可通过降低多代人的大脑同型半胱氨酸水平来改善阿尔茨海默病的病理

Ramon Velazquez, Eric Ferreira, Wendy Winslow, Nikhil Dave, Ignazio S Piras, Marcus Naymik, Matthew J Huentelman, An Tran, Antonella Caccamo, Salvatore Oddo

Lifelong choline supplementation ameliorates Alzheimer's disease pathology and associated cognitive deficits by attenuating microglia activation

终生补充胆碱可通过减弱小胶质细胞活化来改善阿尔茨海默病病理和相关的认知缺陷

Ramon Velazquez, Eric Ferreira, Sara Knowles, Chaya Fux, Alexis Rodin, Wendy Winslow, Salvatore Oddo