Ran Xinru相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Multiomics Mendelian randomization identifies serpin family G member 1 as a chronic obstructive pulmonary disease modulator

多组学孟德尔随机化鉴定出丝氨酸蛋白酶抑制剂家族G成员1是慢性阻塞性肺疾病的调节因子

期刊:Signal Transduction and Targeted Therapy

影响因子:52.7

doi:10.1038/s41392-025-02547-7

Yi, Erkang; Cui, Jieda; Wang, Hairong; Wu, Fan; Hong, Qiyang; Li, Qingyang; Xie, Chengshu; Xu, Huahua; Liu, Yu; Ran, Xinru; Wu, Xiaohui; Wan, Qi; Tang, Gaoying; Zhu, Leqing; Pang, Junling; Zhou, Yumin; Long, Erping; Ran, Pixin

慢性阻塞性肺疾病

发表日期：2026

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Multi-omics reveals cholesterol-driven macrophage metabolic reprogramming and inflammation in chronic obstructive pulmonary disease

多组学揭示胆固醇驱动的巨噬细胞代谢重编程和慢性阻塞性肺疾病中的炎症

期刊:Genome Medicine

影响因子:11.2

doi:10.1186/s13073-025-01591-w

Ran, Xinru; Yang, Zhandong; Cheng, Li; Li, Weidong; Cui, Jieda; Huang, Peiyu; Wang, Zhongfang; Mao, Zhennan; Yi, Erkang; Tian, Yang; Li, Pan; Zhou, Yumin; Ran, Pixin; Guo, Feng

慢性阻塞性肺疾病

代谢重编程

细胞生物学

免疫/内分泌

发表日期：2026

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Long Noncoding RNA Interleukin 6 Antisense RNA 1 Promotes Inflammatory Effects in Lung Macrophages via Exosomes Through the S100A9/TLR4 Pathway in Chronic Obstructive Pulmonary Disease Progression

长链非编码RNA白细胞介素6反义RNA 1通过S100A9/TLR4通路，经由外泌体促进慢性阻塞性肺疾病进展中肺巨噬细胞的炎症反应

影响因子:10.7

doi:10.1002/mco2.70204

Yi, Erkang; Wang, Xiaoyu; Liu, Yu; Wang, Zihui; Bai, Ge; Mei, Xinyue; Wu, Fan; Xie, Chengshu; Li, QiYang; Cao, Weitao; Xu, Huahua; Liu, Xinyuan; Cui, Jieda; Li, Haiqing; Sun, Ruiting; Ran, Xinru; Hong, Wei; Deng, Zhishan; Li, Bing; Zhou, Yumin; Ran, Pixin

慢性阻塞性肺疾病

免疫/内分泌

细胞生物学

发表日期：2025

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An integrated machine learning model of transcriptomic genes in multi-center chronic obstructive pulmonary disease reveals the causal role of TIMP4 in airway epithelial cell.

针对多中心慢性阻塞性肺疾病的转录组基因，一项整合机器学习模型揭示了 TIMP4 在气道上皮细胞中的致病作用

期刊:Respiratory Research

doi:10.1186/s12931-025-03238-1

Yi Erkang, Li Haiqing, Liu Yu, Li Qingyang, Xie Chengshu, Sun Ruining, Wu Fan, Deng Zhishan, Zhou Kunning, Wang Hairong, Ran Xinru, Zhou Yumin, Ran Pixin

细胞生物学

发表日期：2025

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MTMR4 SNVs modulate ion channel degradation and clinical severity in congenital long QT syndrome: insights in the mechanism of action of protective modifier genes

MTMR4 SNVs 调控先天性长QT综合征中的离子通道降解和临床严重程度：对保护性修饰基因作用机制的深入理解

期刊:Cardiovascular Research

影响因子:13.3

doi:10.1093/cvr/cvaa019

Lee, Yee-Ki; Sala, Luca; Mura, Manuela; Rocchetti, Marcella; Pedrazzini, Matteo; Ran, Xinru; Mak, Timothy S H; Crotti, Lia; Sham, Pak C; Torre, Eleonora; Zaza, Antonio; Schwartz, Peter J; Tse, Hung-Fat; Gnecchi, Massimiliano

发表日期：2021

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Coverage and diagnostic yield of Whole Exome Sequencing for the Evaluation of Cases with Dilated and Hypertrophic Cardiomyopathy

全外显子组测序在扩张型和肥厚型心肌病病例评估中的覆盖率和诊断率

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-018-29263-3

Mak, Timothy Shin Heng; Lee, Yee-Ki; Tang, Clara S; Hai, JoJo S H; Ran, Xinru; Sham, Pak-Chung; Tse, Hung-Fat

发表日期：2018

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