Genome-wide analysis in 756,646 individuals provides first genetic evidence that ACE2 expression influences COVID-19 risk and yields genetic risk scores predictive of severe disease
对 756,646 名个体进行的全基因组分析首次提供了遗传学证据，表明 ACE2 表达会影响 COVID-19 的风险，并产生了可预测重症的遗传风险评分。
期刊:
影响因子:
doi:10.1101/2020.12.14.20248176
Horowitz, J E; Kosmicki, J A; Damask, A; Sharma, D; Roberts, G H L; Justice, A E; Banerjee, N; Coignet, M V; Yadav, A; Leader, J B; Marcketta, A; Park, D S; Lanche, R; Maxwell, E; Knight, S C; Bai, X; Guturu, H; Sun, D; Baltzell, A; Kury, F S P; Backman, J D; Girshick, A R; O'Dushlaine, C; McCurdy, S R; Partha, R; Mansfield, A J; Turissini, D A; Li, A H; Zhang, M; Mbatchou, J; Watanabe, K; Gurski, L; McCarthy, S E; Kang, H M; Dobbyn, L; Stahl, E; Verma, A; Sirugo, G; Ritchie, M D; Jones, M; Balasubramanian, S; Siminovitch, K; Salerno, W J; Shuldiner, A R; Rader, D J; Mirshahi, T; Locke, A E; Marchini, J; Overton, J D; Carey, D J; Habegger, L; Cantor, M N; Rand, K A; Hong, E L; Reid, J G; Ball, C A; Baras, A; Abecasis, G R; Ferreira, M A
