日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Intranasal immunization with live-attenuated RSV-vectored SARS-CoV-2 vaccines elicits antigen-specific systemic and mucosal immunity and protects against viral challenge and natural infection

鼻内接种减毒活病毒载体SARS-CoV-2疫苗可诱导抗原特异性全身和黏膜免疫,并能抵抗病毒攻击和自然感染。

Botta, Davide; Schultz, Michael D; Silva-Sanchez, Aaron; Kalange, Davies; Akther, Jobaida; Zhou, Fen; Tipper, Jennifer L; Yang, Guang; Schaefers, Levi T; Barkley, Courtney A; Qiu, Shihong; Foote, Jeremy B; Tioni, Mariana F; Weiss, Christopher M; Phan, Shannon I; Green, Todd J; Leal, Sixto M Jr; Harrod, Kevin S; King, Rodney G; Moore, Martin L; Randall, Troy D; Tang, Roderick S; Lund, Frances E

IFNγ-induced IRF1 synergizes with TLR7 signals to tune the IRF4-IRF8 axis and drive pathogenic effector B cell fate

IFNγ诱导的IRF1与TLR7信号协同作用,调节IRF4-IRF8轴,并驱动致病性效应B细胞的命运。

Owiredu, Eddie-Williams; Denslow, Ashley J; Chen, Suki; Mousseau, Betty; Foote, Jeremy B; Yang, Guang; Peel, Jessica N; Burnham, Rebecca; Browning, Kelsey; Scharer, Christopher D; Randall, Troy D; Zumaquero-Martinez, Esther; Lund, Frances E

Topography of the HLA-A protein enforces shared and convergent immunodominant B cell and antibody alloresponses in transplant recipients

HLA-A蛋白的拓扑结构决定了移植受者体内共享且趋同的免疫优势B细胞和抗体同种异体反应。

Killian, John T Jr; King, R Glenn; Lucander, Aaron C K; Kizziah, James L; Fucile, Christopher F; Diaz-Avalos, Ruben; Qiu, Shihong; Silva-Sanchez, Aaron; Mousseau, Betty J; Macon, Kevin J; Callahan, Amanda R; Yang, Guang; Hossain, M Emon; Akther, Jobaida; Good, Daryl B; Kelso, Susan; Houp, Julie A; Rosenblum, Frida; Porrett, Paige M; Ong, Song C; Kumar, Vineeta; Saphire, Erica Ollmann; Kearney, John F; Randall, Troy D; Rosenberg, Alexander F; Green, Todd J; Lund, Frances E

Aryl Hydrocarbon Receptor Activation Promotes Effector CD4+ T Cell Homeostasis and Restrains Salt-Sensitive Hypertension.

芳烃受体激活促进效应 CD4+ T 细胞稳态并抑制盐敏感性高血压

Molina Patrick A, Edell Claudia J, Dunaway Luke S, Kellum Cailin E, Muir Rachel Q, Jennings Melissa S, Colson Jackson C, De Miguel Carmen, Rhoads Megan K, Buzzelli Ashlyn A, Harrington Laurie E, Meza-Perez Selene, Randall Troy D, Botta Davide, Müller Dominik N, Pollock David M, Maynard Craig L, Pollock Jennifer S

Mucosal delivery of influenza antigens using a replication deficient adenovirus supports broadly reactive antibody responses and heterologous viral immunity in the respiratory tract of animals.

利用复制缺陷型腺病毒进行流感抗原的粘膜递送,可支持动物呼吸道内广泛的抗体反应和异源病毒免疫。

Schultz Michael D, Botta Davide, Silva-Sanchez Aaron, Cheatwood Isabella R, Kalange Davies, Terapane Sarah M, Lucander Aaron C K, Zhou Fen, Akther Jobaida, Yang Guang, Cockerham Mary E, Stover William O, Hall John A, Yadav Dinesh, Fox Douglas M, Dominguez Francisco, Leal Sixto M Jr, Foote Jeremy B, Harrod Kevin S, Randall Troy D, Rice Adrian E, Gabitzsch Elizabeth S, Lund Frances E

Immunity in adipose tissues: Cutting through the fat

脂肪组织中的免疫力:突破脂肪层

Randall, Troy D; Meza-Perez, Selene

HLA topography enforces shared and convergent immunodominant B cell and antibody alloresponses in transplant recipients

HLA拓扑结构决定了移植受者体内共享且趋同的免疫优势B细胞和抗体同种异体反应。

Killian, John T; Glenn King, R; Lucander, Aaron C K; Kizziah, James L; Fucile, Christopher F; Diaz-Avalos, Ruben; Qiu, Shihong; Silva-Sanchez, Aaron; Mousseau, Betty J; Macon, Kevin J; Callahan, Amanda R; Yang, Guang; Emon Hossain, M; Akther, Jobaida; Good, Daryl B; Kelso, Susan; Houp, Julie A; Rosenblum, Frida; Porrett, Paige M; Ong, Song C; Kumar, Vineeta; Saphire, Erica Ollmann; Kearney, John F; Randall, Troy D; Rosenberg, Alexander F; Green, Todd J; Lund, Frances E

Spiking SARS-CoV-2 antiviral immunity in the respiratory tract

增强呼吸道中SARS-CoV-2抗病毒免疫力

Silva-Sanchez, Aaron; Randall, Troy D

Chitinase-3-like 1 regulates T(H)2 cells, T(FH) cells and IgE responses to helminth infection

几丁质酶-3样蛋白1调节T(H)2细胞、T(FH)细胞和IgE对蠕虫感染的反应

Curtiss, Miranda L; Rosenberg, Alexander F; Scharer, Christopher D; Mousseau, Betty; Benavides, Natalia A Ballesteros; Bradley, John E; León, Beatriz; Steele, Chad; Randall, Troy D; Lund, Frances E

Neutralization of TGFβ Improves Tumor Immunity and Reduces Tumor Progression in Ovarian Carcinoma

TGFβ中和作用可改善肿瘤免疫力并减缓卵巢癌的肿瘤进展

Roane, Brandon M; Meza-Perez, Selene; Katre, Ashwini A; Goldsberry, Whitney N; Randall, Troy D; Norian, Lyse A; Birrer, Michael J; Arend, Rebecca C