日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

New Ref-1/APE1 targeted inhibitors demonstrating improved potency for clinical applications in multiple cancer types

新型 Ref-1/APE1 靶向抑制剂在多种癌症类型的临床应用中表现出更高的疗效

Silpa Gampala, Hye-Ran Moon, Randall Wireman, Jacqueline Peil, Sonia Kiran, Dana K Mitchell, Kylee Brewster, Henry Mang, Andi Masters, Christine Bach, Whitney Smith-Kinnamen, Emma H Doud, Ratan Rai, Amber L Mosley, Sara K Quinney, D Wade Clapp, Chafiq Hamdouchi, James Wikel, Chi Zhang, Bumsoo Han, M

RelA Is an Essential Target for Enhancing Cellular Responses to the DNA Repair/Ref-1 Redox Signaling Protein and Restoring Perturbated Cellular Redox Homeostasis in Mouse PDAC Cells

RelA 是增强细胞对 DNA 修复/Ref-1 氧化还原信号蛋白的反应和恢复小鼠 PDAC 细胞中受干扰的细胞氧化还原稳态的重要靶点

Mahmut Mijit, Randall Wireman, Lee Armstrong, Silpa Gampala, Zonera Hassan, Christian Schneeweis, Guenter Schneider, Chi Zhang, Melissa L Fishel, Mark R Kelley

Small molecule activation of apurinic/apyrimidinic endonuclease 1 reduces DNA damage induced by cisplatin in cultured sensory neurons

小分子激活脱嘌呤/脱嘧啶内切酶 1 可减少培养的感觉神经元中顺铂引起的 DNA 损伤

Millie M Georgiadis, Qiujia Chen, Jingwei Meng, Chunlu Guo, Randall Wireman, April Reed, Michael R Vasko, Mark R Kelley