日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond

阿片类药物成瘾的多性状全基因组关联研究:OPRM1 及其他

Gaddis, Nathan; Mathur, Ravi; Marks, Jesse; Zhou, Linran; Quach, Bryan; Waldrop, Alex; Levran, Orna; Agrawal, Arpana; Randesi, Matthew; Adelson, Miriam; Jeffries, Paul W; Martin, Nicholas G; Degenhardt, Louisa; Montgomery, Grant W; Wetherill, Leah; Lai, Dongbing; Bucholz, Kathleen; Foroud, Tatiana; Porjesz, Bernice; Runarsdottir, Valgerdur; Tyrfingsson, Thorarinn; Einarsson, Gudmundur; Gudbjartsson, Daniel F; Webb, Bradley Todd; Crist, Richard C; Kranzler, Henry R; Sherva, Richard; Zhou, Hang; Hulse, Gary; Wildenauer, Dieter; Kelty, Erin; Attia, John; Holliday, Elizabeth G; McEvoy, Mark; Scott, Rodney J; Schwab, Sibylle G; Maher, Brion S; Gruza, Richard; Kreek, Mary Jeanne; Nelson, Elliot C; Thorgeirsson, Thorgeir; Stefansson, Kari; Berrettini, Wade H; Gelernter, Joel; Edenberg, Howard J; Bierut, Laura; Hancock, Dana B; Johnson, Eric Otto

OPRD1 SNPs associated with opioid addiction are cis-eQTLs for the phosphatase and actin regulator 4 gene, PHACTR4, a mediator of cytoskeletal dynamics

与阿片类药物成瘾相关的 OPRD1 SNP 是磷酸酶和肌动蛋白调节因子 4 基因 (PHACTR4) 的顺式 eQTL,PHACTR4 是细胞骨架动力学的介质。

Levran, Orna; Randesi, Matthew; Adelson, Miriam; Kreek, Mary Jeanne

Genotype Pattern Mining for Pairs of Interacting Variants Underlying Digenic Traits

基因型模式挖掘:识别双基因性状背后的相互作用变异对

Okazaki, Atsuko; Horpaopan, Sukanya; Zhang, Qingrun; Randesi, Matthew; Ott, Jurg

Association of Serotonin Transporter (SERT) Polymorphisms with Opioid Dependence and Dimensional Aspects of Cocaine Use in a Caucasian Cohort of Opioid Users

在白种人阿片类药物使用者队列中,血清素转运蛋白(SERT)多态性与阿片类药物依赖及可卡因使用维度之间的关联

Yuferov, Vadim; Butelman, Eduardo R; Randesi, Matthew; van den Brink, Wim; Blanken, Peter; van Ree, Jan M; Kreek, Mary Jeanne

Variants of opioid genes and response to treatment of opioid use disorder with buprenorphine-naloxone versus extended-release naltrexone in Caucasians.

白种人中阿片类基因变异与使用丁丙诺啡-纳洛酮治疗阿片类药物使用障碍和使用缓释纳曲酮治疗阿片类药物使用障碍的反应

Randesi Matthew, Rotrosen John, Nunes Edward V, Lee Joshua D, Novo Patricia, Levran Orna, Ott Jurg, Pavlicova Martina, Scodes Jennifer, Kreek Mary Jeanne

A 3' UTR SNP rs885863, a cis-eQTL for the circadian gene VIPR2 and lincRNA 689, is associated with opioid addiction

位于 3' UTR 的 SNP rs885863,是昼夜节律基因 VIPR2 和 lincRNA 689 的顺式 eQTL,与阿片类药物成瘾相关。

Levran, Orna; Randesi, Matthew; Rotrosen, John; Ott, Jurg; Adelson, Miriam; Kreek, Mary Jeanne

Association of variants of prodynorphin promoter 68-bp repeats in caucasians with opioid dependence diagnosis: Effect on age trajectory of heroin use

高加索人中强啡肽原启动子68bp重复序列变异与阿片类药物依赖诊断的关联:对海洛因使用年龄轨迹的影响

Yuferov, Vadim; Randesi, Matthew; Butelman, Eduardo R; van den Brink, Wim; Blanken, Peter; van Ree, Jan M; Ott, Jürg; Kreek, Mary Jeanne

VMAT2 gene (SLC18A2) variants associated with a greater risk for developing opioid dependence

VMAT2基因(SLC18A2)变异与阿片类药物依赖风险增加相关

Randesi, Matthew; van den Brink, Wim; Levran, Orna; Blanken, Peter; van Ree, Jan M; Ott, Jurg; Kreek, Mary Jeanne

Sex differences after chronic stress in the expression of opioid-, stress- and neuroplasticity-related genes in the rat hippocampus

慢性应激后大鼠海马中阿片类、应激和神经可塑性相关基因表达的性别差异

Randesi, Matthew; Zhou, Yan; Mazid, Sanoara; Odell, Shannon C; Gray, Jason D; Correa da Rosa, J; McEwen, Bruce S; Milner, Teresa A; Kreek, Mary Jeanne

Oprm1 A112G, a single nucleotide polymorphism, alters expression of stress-responsive genes in multiple brain regions in male and female mice

Oprm1 A112G 是一种单核苷酸多态性,它会改变雄性和雌性小鼠多个脑区中应激反应基因的表达。

Collins, Devon; Randesi, Matthew; da Rosa, Joel Correa; Zhang, Yong; Kreek, Mary Jeanne