日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Nonclinical and clinical characterization of the absorption, metabolism, and excretion of islatravir

伊斯拉曲韦的吸收、代谢和排泄的非临床和临床特征

Fillgrove, Kerry L; Matthews, Randolph P; Lu, Bing; Liang, Yuexia; Patel, Munjal; Liu, Wen; Matthews, Catherine Z; Liu, Yang; Stoch, S Aubrey; Sanchez, Rosa I; Iwamoto, Marian

Pharmacokinetics of Atorvastatin and Metformin after Coadministration with Islatravir in Healthy Adults

健康成人同时服用阿托伐他汀和二甲双胍与伊斯拉曲韦后的药代动力学

McCrea, Jacqueline B; Patel, Munjal; Liu, Yang; Vargo, Ryan; Witter, Rose; Litovsky, Andrew; Stoch, S Aubrey; Iwamoto, Marian; Matthews, Randolph P

A Phase 1 Study to Evaluate the Pharmacokinetic Drug-Drug Interaction Between Islatravir and Methadone in Participants on Stable Methadone Therapy

一项评估伊斯拉曲韦与美沙酮在接受稳定美沙酮治疗的受试者中药代动力学药物相互作用的 I 期研究

Matthews, Randolph P; Ankrom, Wendy; Handy, Whitney; Patel, Munjal; Matthews, Catherine; Xu, Zhiqing; Gravesande, Kezia; Searle, Shawn; Schwartz, Howard; Stoch, S Aubrey; Iwamoto, Marian

Pharmacokinetics of islatravir in participants with moderate hepatic impairment

伊斯拉曲韦在中度肝功能损害患者中的药代动力学研究

Matthews, Randolph P; Patel, Munjal; Liu, Wen; Liu, Yang; Rondón, Juan C; Vargo, Ryan C; Stoch, S Aubrey; Iwamoto, Marian

Safety and Pharmacokinetics of MK-8527 in Adults Without HIV

MK-8527 在非 HIV 感染成人中的安全性和药代动力学

Gillespie, Gillian; Carstens, Russ P; Zang, Xiaowei; Vargo, Ryan; Kapoor, Yash; Bhattacharyya, Arinjita; Denef, Jean-Francois; Reynders, Tom; Vanhoutte, Frédéric; Rottey, Sylvie; Matthews, Randolph P; Stoch, S Aubrey; Iwamoto, Marian

Closing the Last Mile Gap in Access to Multimodality Imaging in Rural Settings: Design of the Imaging Core of the Risk Underlying Rural Areas Longitudinal Study

弥合农村地区多模态影像服务获取的“最后一公里”差距:农村地区潜在风险纵向研究影像核心的设计

Fazlalizadeh, Hooman; Khan, Muhammad Shahzeb; Fox, Ervin R; Douglas, Pamela S; Adams, David; Blaha, Michael J; Daubert, Melissa A; Dunn, Gary; van den Heuvel, Edwin; Kelsey, Michelle D; Martin, Randolph P; Thomas, James D; Thomas, Yngvil; Judd, Suzanne E; Vasan, Ramachandran S; Budoff, Matthew J; Bloomfield, Gerald S

Thorough QT/QTc study to evaluate the effect of a single supratherapeutic dose of islatravir on QTc interval prolongation in healthy adults

一项全面的QT/QTc研究旨在评估单次超治疗剂量伊斯拉曲韦对健康成年人QTc间期延长的影响

Matthews, Randolph P; Liu, Yang; Matthews, Catherine; Butterfield, Kristin L; O'Reilly, Terry; Stoch, S Aubrey; Iwamoto, Marian

Intracellular islatravir-triphosphate half-life supports extended dosing intervals

细胞内伊斯拉曲韦三磷酸盐的半衰期支持延长给药间隔

Zang, Xiaowei; Ankrom, Wendy; Kraft, Walter K; Vargo, Ryan; Stoch, S Aubrey; Iwamoto, Marian; Matthews, Randolph P

A Randomized, Double-Blind, Placebo-Controlled, Phase 1 Trial of Radiopaque Islatravir-Eluting Subdermal Implants for Pre-exposure Prophylaxis Against HIV-1 Infection

一项随机、双盲、安慰剂对照的 I 期临床试验,研究放射性不透光伊斯拉曲韦洗脱皮下植入物用于 HIV-1 感染暴露前预防的疗效

Matthews, Randolph P; Zang, Xiaowei; Barrett, Stephanie E; Koynov, Athanas; Goodey, Adrian; Heimbach, Tycho; Weissler, Vanessa L; Leyssens, Carlien; Reynders, Tom; Xu, Zhiqing; Rottey, Sylvie; Vargo, Ryan; Robertson, Michael N; Stoch, S Aubrey; Iwamoto, Marian

Safety and Pharmacokinetics of Islatravir in Individuals with Severe Renal Insufficiency

伊斯拉曲韦在严重肾功能不全患者中的安全性和药代动力学

Matthews, Randolph P; Cao, Youfang; Patel, Munjal; Weissler, Vanessa L; Bhattacharyya, Arinjita; De Lepeleire, Inge; Last, Stefanie; Rondon, Juan C; Vargo, Ryan; Stoch, S Aubrey; Iwamoto, Marian