日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Exploring the "misfolding problem" by systematic discovery and analysis of functional-but-degraded proteins

通过系统地发现和分析功能性但已降解的蛋白质,探索“错误折叠问题”。

Flagg, Matthew P; Lam, Breanna; Lam, Darren K; Le, Tiffany M; Kao, Andy; Slaiwa, Yousif I; Hampton, Randolph Y

An autonomous, but INSIG-modulated, role for the sterol sensing domain in mallostery-regulated ERAD of yeast HMG-CoA reductase

酵母HMG-CoA还原酶甾醇感应结构域在mallotstery调控的ERAD过程中发挥自主但受INSIG调控的作用

Wangeline, Margaret A; Hampton, Randolph Y

Inner-nuclear-membrane-associated degradation employs Dfm1-independent retrotranslocation and alleviates misfolded transmembrane-protein toxicity

内核膜相关降解利用 Dfm1 独立的逆转录易位并减轻错误折叠的跨膜蛋白毒性

Matthew P Flagg, Margaret A Wangeline, Sarah R Holland, Sascha H Duttke, Christopher Benner, Sonya Neal, Randolph Y Hampton

Direct involvement of Hsp70 ATP hydrolysis in Ubr1-dependent quality control.

Hsp70 ATP水解直接参与Ubr1依赖性质量控制

Singh Amanjot, Vashistha Nidhi, Heck Jarrod, Tang Xin, Wipf Peter, Brodsky Jeffrey L, Hampton Randolph Y

Assays for protein retrotranslocation in ERAD

ERAD中蛋白质逆向转运的检测

Neal, Sonya; Duttke, Sascha H; Hampton, Randolph Y

Systematic Gene-to-Phenotype Arrays: A High-Throughput Technique for Molecular Phenotyping

系统基因到表型阵列:一种用于分子表型分析的高通量技术

Philipp A Jaeger, Lilia Ornelas, Cameron McElfresh, Lily R Wong, Randolph Y Hampton, Trey Ideker

The Dfm1 Derlin Is Required for ERAD Retrotranslocation of Integral Membrane Proteins

Dfm1 Derlin 是 ERAD 膜蛋白逆转录转位所必需的

Sonya Neal, Philipp A Jaeger, Sascha H Duttke, Christopher Benner, Christopher K Glass, Trey Ideker, Randolph Y Hampton

Proteostatic Tactics in the Strategy of Sterol Regulation

甾醇调节策略中的蛋白质稳态策略

Wangeline, Margaret A; Vashistha, Nidhi; Hampton, Randolph Y

Insulin-induced gene protein (INSIG)-dependent sterol regulation of Hmg2 endoplasmic reticulum-associated degradation (ERAD) in yeast.

酵母中胰岛素诱导基因蛋白(INSIG)依赖的甾醇调节Hmg2内质网相关降解(ERAD)

Theesfeld Chandra L, Hampton Randolph Y

Protein quality control as a strategy for cellular regulation: lessons from ubiquitin-mediated regulation of the sterol pathway

蛋白质质量控制作为细胞调控策略:从泛素介导的甾醇途径调控中汲取的启示

Hampton, Randolph Y; Garza, Renee M