日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Impact of alemtuzumab-mediated lymphocyte depletion on SIV reservoir establishment and persistence

阿仑单抗介导的淋巴细胞耗竭对SIV病毒库建立和持续存在的影响

Benjamin Varco-Merth ,Morgan Chaunzwa ,Derick M Duell ,Alejandra Marenco ,William Goodwin ,Rachel Dannay ,Michael Nekorchuk ,Danica Shao ,Kathleen Busman-Sahay ,Christine M Fennessey ,Lorna Silipino ,Michael Hull ,William J Bosche ,Randy Fast ,Kelli Oswald ,Rebecca Shoemaker ,Rachele Bochart ,Rhonda MacAllister ,Caralyn S Labriola ,Jeremy V Smedley ,Michael K Axthelm ,Miles P Davenport ,Paul T Edlefsen ,Jacob D Estes ,Brandon F Keele ,Jeffrey D Lifson ,Sharon R Lewin ,Louis J Picker ,Afam A Okoye

Early antiretroviral therapy in SIV-infected rhesus macaques reveals a multiphasic, saturable dynamic accumulation of the rebound competent viral reservoir

在感染SIV的恒河猴中,早期抗逆转录病毒疗法揭示了具有反弹能力的病毒库的多相、可饱和的动态积累过程。

Brandon F Keele ,Afam A Okoye ,Christine M Fennessey ,Benjamin Varco-Merth ,Taina T Immonen ,Emek Kose ,Andrew Conchas ,Mykola Pinkevych ,Leslie Lipkey ,Laura Newman ,Agatha Macairan ,Marjorie Bosche ,William J Bosche ,Brian Berkemeier ,Randy Fast ,Mike Hull ,Kelli Oswald ,Rebecca Shoemaker ,Lorna Silipino ,Robert J Gorelick ,Derick Duell ,Alejandra Marenco ,William Brantley ,Jeremy Smedley ,Michael Axthelm ,Miles P Davenport ,Jeffrey D Lifson ,Louis J Picker

Antibody-mediated depletion of viral reservoirs is limited in SIV-infected macaques treated early with antiretroviral therapy

在接受早期抗逆转录病毒治疗的SIV感染猕猴中,抗体介导的病毒库清除作用有限。

Adrienne E Swanstrom ,Taina T Immonen ,Kelli Oswald ,Cathi Pyle ,James A Thomas ,William J Bosche ,Lorna Silipino ,Michael Hull ,Laura Newman ,Vicky Coalter ,Adam Wiles ,Rodney Wiles ,Jacob Kiser ,David R Morcock ,Rebecca Shoemaker ,Randy Fast ,Matthew W Breed ,Joshua Kramer ,Duncan Donohue ,Tyler Malys ,Christine M Fennessey ,Charles M Trubey ,Claire Deleage ,Jacob D Estes ,Jeffrey D Lifson ,Brandon F Keele ,Gregory Q Del Prete

TLR7 agonist administration to SIV-infected macaques receiving early initiated cART does not induce plasma viremia

对接受早期 cART 治疗的 SIV 感染恒河猴施用 TLR7 激动剂不会诱发血浆病毒血症

Gregory Q Del Prete, W Gregory Alvord, Yuan Li, Claire Deleage, Mukta Nag, Kelli Oswald, James A Thomas, Cathi Pyle, William J Bosche, Vicky Coalter, Adam Wiles, Rodney Wiles, Brian Berkemeier, Michael Hull, Elizabeth Chipriano, Lorna Silipino, Randy Fast, Jacob Kiser, Rebecca Kiser, Tyler Malys, Jo

Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment viral rebound

早期抗逆转录病毒疗法可限制SIV病毒库的建立,从而延缓或阻止治疗后病毒反弹。

Afam A Okoye ,Scott G Hansen ,Mukta Vaidya ,Yoshinori Fukazawa ,Haesun Park ,Derick M Duell ,Richard Lum ,Colette M Hughes ,Abigail B Ventura ,Emily Ainslie ,Julia C Ford ,David Morrow ,Roxanne M Gilbride ,Alfred W Legasse ,Joseph Hesselgesser ,Romas Geleziunas ,Yuan Li ,Kelli Oswald ,Rebecca Shoemaker ,Randy Fast ,William J Bosche ,Bhavesh R Borate ,Paul T Edlefsen ,Michael K Axthelm ,Louis J Picker ,Jeffrey D Lifson

CD8(+) Lymphocytes Are Required for Maintaining Viral Suppression in SIV-Infected Macaques Treated with Short-Term Antiretroviral Therapy

CD8(+)淋巴细胞对于接受短期抗逆转录病毒治疗的SIV感染猕猴维持病毒抑制是必需的

Emily K Cartwright ,Lori Spicer ,S Abigail Smith ,David Lee ,Randy Fast ,Sara Paganini ,Benton O Lawson ,Melon Nega ,Kirk Easley ,Joern E Schmitz ,Steven E Bosinger ,Mirko Paiardini ,Ann Chahroudi ,Thomas H Vanderford ,Jacob D Estes ,Jeffrey D Lifson ,Cynthia A Derdeyn ,Guido Silvestri

Elevated Plasma Viral Loads in Romidepsin-Treated Simian Immunodeficiency Virus-Infected Rhesus Macaques on Suppressive Combination Antiretroviral Therapy

接受罗米地辛治疗的感染猴免疫缺陷病毒的恒河猴在接受抑制性联合抗逆转录病毒治疗时血浆病毒载量升高

Gregory Q Del Prete, Kelli Oswald, Abigail Lara, Rebecca Shoemaker, Jeremy Smedley, Rhonda Macallister, Vicky Coalter, Adam Wiles, Rodney Wiles, Yuan Li, Randy Fast, Rebecca Kiser, Bing Lu, Jim Zheng, W Gregory Alvord, Charles M Trubey, Michael Piatak Jr, Claire Deleage, Brandon F Keele, Jacob D Est

Selection of unadapted, pathogenic SHIVs encoding newly transmitted HIV-1 envelope proteins

选择编码新传播的 HIV-1 包膜蛋白的未适应致病 SHIV

Gregory Q Del Prete, Braiden Eilers, Brian Moldt, Brandon F Keele, Jacob D Estes, Anthony Rodriguez, Marissa Sampias, Kelli Oswald, Randy Fast, Charles M Trubey, Elena Chertova, Jeremy Smedley, Celia C LaBranche, David C Montefiori, Dennis R Burton, George M Shaw, Marty Markowitz, Michael Piatak Jr,

Effect of suberoylanilide hydroxamic acid (SAHA) administration on the residual virus pool in a model of combination antiretroviral therapy-mediated suppression in SIVmac239-infected indian rhesus macaques

辛二酰苯胺异羟肟酸 (SAHA) 给药对 SIVmac239 感染印度恒河猴联合抗逆转录病毒疗法介导抑制模型中残留病毒库的影响

Gregory Q Del Prete, Rebecca Shoemaker, Kelli Oswald, Abigail Lara, Charles M Trubey, Randy Fast, Douglas K Schneider, Rebecca Kiser, Vicky Coalter, Adam Wiles, Rodney Wiles, Brandi Freemire, Brandon F Keele, Jacob D Estes, Octavio A Quiñones, Jeremy Smedley, Rhonda Macallister, Rosa I Sanchez, John