Protective Effects of Amauroderma rugosum on Doxorubicin-Induced Cardiotoxicity through Suppressing Oxidative Stress, Mitochondrial Dysfunction, Apoptosis, and Activating Akt/mTOR and Nrf2/HO-1 Signaling Pathways
皱叶紫菀通过抑制氧化应激、线粒体功能障碍、细胞凋亡以及激活Akt/mTOR和Nrf2/HO-1信号通路,对阿霉素诱导的心脏毒性发挥保护作用
期刊:Oxidative Medicine and Cellular Longevity
影响因子:
doi:10.1155/2022/9266178
Li, Jingjing; Cheng, Yanfen; Li, Renkai; Wu, Xiaoping; Zheng, Chengwen; Shiu, Polly Ho-Ting; Chan, Jacqueline Cho-Ki; Rangsinth, Panthakarn; Liu, Conghui; Leung, Susan Wai-Sum; Lee, Simon Ming-Yuen; Zhang, Chen; Fu, Chaomei; Zhang, Jinming; Cheung, Timothy Man-Yau; Leung, George Pak-Heng
凋亡
mTOR
表观遗传
氧化应激
Apoptosis
信号转导
线粒体
细胞生物学
毒理研究