Discovery of cyclopropyl chromane-derived pyridopyrazine-1,6-dione γ-secretase modulators with robust central efficacy
发现具有显著中枢活性的环丙基色满衍生的吡啶并吡嗪-1,6-二酮γ-分泌酶调节剂
期刊:Medchemcomm
影响因子:
doi:10.1039/c6md00406g
Pettersson, Martin; Johnson, Douglas S; Rankic, Danica A; Kauffman, Gregory W; Am Ende, Christopher W; Butler, Todd W; Boscoe, Brian; Evrard, Edelweiss; Helal, Christopher J; Humphrey, John M; Stepan, Antonia F; Stiff, Cory M; Yang, Eddie; Xie, Longfei; Bales, Kelly R; Hajos-Korcsok, Eva; Jenkinson, Stephen; Pettersen, Betty; Pustilnik, Leslie R; Ramirez, David S; Steyn, Stefanus J; Wood, Kathleen M; Verhoest, Patrick R
