A coding single nucleotide polymorphism in the interleukin-6 receptor enhances IL-6 signalling in CD4 T cells and predicts treatment response to tocilizumab in giant cell arteritis
白细胞介素-6受体编码单核苷酸多态性增强CD4 T细胞中IL-6信号传导，并可预测巨细胞动脉炎患者对托珠单抗的治疗反应。
期刊:Annals of the Rheumatic Diseases
影响因子:20.6
doi:10.1016/j.ard.2025.01.049
Zorc, Robert; Redmond, Christopher; Sylvester, McKella; Maclean, Mary; Yamamoto de Almeida, Luciana; Quinn, Kaitlin A; Tomelleri, Alessandro; Campochiaro, Corrado; Dagna, Lorenzo; Gutierrez-Rodrigues, Fernanda; Wells, Kristina V; Rankin, Cameron; Hait, Sabrina Helmold; Palmer, Chloe; Corty, Robert; Bick, Alexander; Lambert, Kathi; Buckner, Jane H; O'Shea, John J; Park, Jin Kyun; Gadina, Massimo; Grayson, Peter C
T细胞
信号转导
T细胞
细胞生物学
IL-6
CD4
免疫/内分泌
