日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Intranasal Human NSC-Derived EVs Therapy Can Restrain Inflammatory Microglial Transcriptome, and NLRP3 and cGAS-STING Signalling, in Aged Hippocampus

鼻内给予人神经干细胞来源的细胞外囊泡疗法可以抑制老年海马体中炎症性小胶质细胞的转录组以及NLRP3和cGAS-STING信号通路

期刊:Journal of Extracellular Vesicles
影响因子:14.5
doi:10.1002/jev2.70232
Madhu, Leelavathi N; Kodali, Maheedhar; Rao, Shama; Attaluri, Sahithi; Upadhya, Raghavendra; Shankar, Goutham; Shuai, Bing; Somayaji, Yogish; Ganesh, Shruthi V; Kumar, Vignesh S; James, Jeswin E; Shetty, Padmashri A; LeMaire, Avery; Rao, Xiaolan; Cai, James J; Shetty, Ashok K
胶质细胞
发育与干细胞
炎症
炎症/感染
信号转导
STING
cGAS-STING
LRP3
Human
干细胞
NLRP3
囊泡
细胞生物学
Hippo
发表日期：2026
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Intranasal Human NSC-Derived EVs Therapy Can Restrain Inflammatory Microglial Transcriptome, and NLRP3 and cGAS-STING Signaling, in Aged Hippocampus

鼻内给予人神经干细胞来源的细胞外囊泡疗法可以抑制老年海马体中炎症性小胶质细胞的转录组以及NLRP3和cGAS-STING信号通路

期刊:
影响因子:
doi:10.1101/2025.03.02.641082
Madhu, Leelavathi N; Kodali, Maheedhar; Rao, Shama; Attaluri, Sahithi; Upadhya, Raghavendra; Shankar, Goutham; Shuai, Bing; Somayaji, Yogish; Ganesh, Shruthi V; Kumar, Vignesh S; James, Jeswin E; Shetty, Padmashri; LeMaire, Avery; Rao, Xiaolan; Cai, James J; Shetty, Ashok K
胶质细胞
发育与干细胞
炎症
炎症/感染
信号转导
STING
cGAS-STING
LRP3
Human
干细胞
NLRP3
囊泡
细胞生物学
Hippo
发表日期：2026
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Extracellular vesicles from hiPSC-derived NSCs protect human neurons against Aβ-42 oligomers induced neurodegeneration, mitochondrial dysfunction and tau phosphorylation

来自hiPSC衍生的神经干细胞的细胞外囊泡可保护人类神经元免受Aβ-42寡聚体诱导的神经退行性变、线粒体功能障碍和tau蛋白磷酸化。

期刊:Stem Cell Research & Therapy
影响因子:7.3
doi:10.1186/s13287-025-04324-3
Rao, Shama; Madhu, Leelavathi N; Babu, Roshni Sara; Shankar, Goutham; Kotian, Sanya; Nagarajan, Advaidhaa; Upadhya, Raghavendra; Narvekar, Esha; Cai, James J; Shetty, Ashok K
囊泡
发育与干细胞
信号转导
神经科学
线粒体
干细胞
磷酸化
细胞生物学
发表日期：2025
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Transcriptomic and epigenetic analysis of various cell types affected by amyloid‐beta oligomers in the hippocampus of mice during aging

对衰老小鼠海马中受β-淀粉样蛋白寡聚体影响的各种细胞类型的转录组学和表观遗传学分析

期刊:Aging Cell
影响因子:7.1
doi:10.1111/acel.14398
Kodali, Maheedhar; Madhu, Leelavathi N; Somayaji, Yogish; Attaluri, Sahithi; Huard, Charles; Panda, Prashanta Kumar; Shankar, Goutham; Rao, Shama; Shuai, Bing; Gonzalez, Jenny J; Oake, Chris; Hering, Catherine; Babu, Roshni Sara; Kotian, Sanya; Shetty, Ashok K; Leduc, Klarissa
细胞生物学
衰老
表观遗传
发表日期：2025
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Extracellular vesicles from human-induced pluripotent stem cell-derived neural stem cells alleviate proinflammatory cascades within disease-associated microglia in Alzheimer's disease.

人诱导多能干细胞衍生的神经干细胞产生的细胞外囊泡可减轻阿尔茨海默病中与疾病相关的小胶质细胞内的促炎级联反应

期刊:Journal of Extracellular Vesicles
影响因子:14.5
doi:10.1002/jev2.12519
Madhu Leelavathi N, Kodali Maheedhar, Upadhya Raghavendra, Rao Shama, Somayaji Yogish, Attaluri Sahithi, Shuai Bing, Kirmani Maha, Gupta Shreyan, Maness Nathaniel, Rao Xiaolan, Cai James J, Shetty Ashok K
神经科学
囊泡
发表日期：2024
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Intranasally Administered EVs from hiPSC-derived NSCs Alter the Transcriptomic Profile of Activated Microglia and Conserve Brain Function in an Alzheimer's Model

鼻内给药的源自hiPSC的神经干细胞来源的细胞外囊泡可改变活化小胶质细胞的转录组谱，并在阿尔茨海默病模型中维持脑功能。

期刊:
影响因子:
doi:10.1101/2024.01.18.576313
Madhu, Leelavathi N; Kodali, Maheedhar; Upadhya, Raghavendra; Rao, Shama; Shuai, Bing; Somayaji, Yogish; Attaluri, Sahithi; Kirmani, Maha; Gupta, Shreyan; Maness, Nathaniel; Rao, Xiaolan; Cai, James; Shetty, Ashok K
细胞生物学
发育与干细胞
神经科学
胶质细胞
阿尔茨海默症
囊泡
干细胞
发表日期：2024
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Investigation of the hydration process and biological activity of a novel nanosilver incorporated dicalcium silicate based retrograde filling material

对一种新型纳米银掺杂硅酸二钙基逆行充填材料的水化过程和生物活性进行研究

期刊:PeerJ
影响因子:2.4
doi:10.7717/peerj.14632
Dsouza, Teena; Shetty, Aditya; Kini, Sudarshan; Shetty, Veena; Rao, Shama; Payaradka, Rajesha; Satheesan, Nijil; Dsouza, Neevan; Shetty, Heeresh
发表日期：2023
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Proficiency of Extracellular Vesicles From hiPSC-Derived Neural Stem Cells in Modulating Proinflammatory Human Microglia: Role of Pentraxin-3 and miRNA-21-5p

hiPSC衍生神经干细胞来源的细胞外囊泡在调节促炎性人小胶质细胞中的作用：五聚蛋白-3和miRNA-21-5p的作用

期刊:Frontiers in Molecular Neuroscience
影响因子:3.8
doi:10.3389/fnmol.2022.845542
Upadhya, Raghavendra; Madhu, Leelavathi N; Rao, Shama; Shetty, Ashok K
Human
细胞生物学
发育与干细胞
胶质细胞
囊泡
干细胞
miRNA
发表日期：2022
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Drug Release and Cytotoxicity of Hyaluronic Acid and Zinc Oxide Gels, An In-Vitro Study

透明质酸和氧化锌凝胶的药物释放和细胞毒性：一项体外研究

期刊:Designed Monomers and Polymers
影响因子:2.3
doi:10.1080/15685551.2022.2099647
Lanka, Jaahnavi; Kumar, Santhosh; B, Mohana Kumar; Rao, Shama; Gadag, Shivaprasad; Nayak, Usha Y
细胞生物学
毒理研究
发表日期：2022
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Comparison of Cellular and Differentiation Characteristics of Mesenchymal Stem Cells Derived from Human Gingiva and Periodontal Ligament

人牙龈和牙周膜间充质干细胞的细胞和分化特征比较

期刊:Journal of International Society of Preventive and Community Dentistry
影响因子:2.1
doi:10.4103/jispcd.JISPCD_259_21
Subba, Tarona A; Varma, Sudhir; Thomas, Biju; Rao, Shama; Kumar, Mohana; Talwar, Avaneendra; Shashidhar, Keerthan
细胞生物学
发育与干细胞
Human
干细胞
发表日期：2022
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