日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Automated patch-clamp recordings for detecting activators and inhibitors of the epithelial sodium channel (ENaC)

用于检测上皮钠通道 (ENaC) 激活剂和抑制剂的自动膜片钳记录

Sure, Florian; Rapedius, Markus; Diakov, Alexei; Bertog, Marko; Obergrussberger, Alison; Fertig, Niels; Korbmacher, Christoph; Ilyaskin, Alexandr V

Lysosomal Ion Channels and Transporters: Recent Findings, Therapeutic Potential, and Technical Approaches

溶酶体离子通道和转运蛋白:最新发现、治疗潜力和技术方法

Kondratskyi, Artem; Bazzone, Andre; Rapedius, Markus; Zerlotti, Rocco; Masson, Bastien; Sadanandan, Nidish Ponath; Parker, Joanne L; Santinho, Alexandre; Moutia, Marine; Thiam, Abdou Rachid; Kemp, Arlene; Seibertz, Fitzwilliam; Murciano, Nicoletta; Friis, Søren; Becker, Nadine; Obergrussberger, Alison; Barthmes, Maria; George, Cecilia; George, Michael; Dalrymple, David; Gasnier, Bruno; Newstead, Simon; Grimm, Christian; Fertig, Niels

Atrial fibrillation-associated electrical remodelling in human induced pluripotent stem cell-derived atrial cardiomyocytes: a novel pathway for antiarrhythmic therapy development

人类诱导性多能干细胞来源的心房心肌细胞中的心房颤动相关电重塑:抗心律失常治疗发展的新途径

Fitzwilliam Seibertz, Tony Rubio, Robin Springer, Fiona Popp, Melanie Ritter, Aiste Liutkute, Lena Bartelt, Lea Stelzer, Fereshteh Haghighi, Jan Pietras, Hendrik Windel, Núria Díaz I Pedrosa, Markus Rapedius, Yannic Doering, Richard Solano, Robin Hindmarsh, Runzhu Shi, Malte Tiburcy, Tobias Bruegman

Electrophysiological and calcium-handling development during long-term culture of human-induced pluripotent stem cell-derived cardiomyocytes

人类诱导多能干细胞衍生的心肌细胞长期培养过程中的电生理和钙处理发展

Fitzwilliam Seibertz #, Henry Sutanto #, Rebekka Dülk, Julius Ryan D Pronto, Robin Springer, Markus Rapedius, Aiste Liutkute, Melanie Ritter, Philipp Jung, Lea Stelzer, Luisa M Hüsgen, Marie Klopp, Tony Rubio, Funsho E Fakuade, Fleur E Mason, Nico Hartmann, Steffen Pabel, Katrin Streckfuss-Bömeke, L

A high-throughput electrophysiology assay to study the response of PIEZO1 to mechanical stimulation

利用高通量电生理检测方法研究PIEZO1对机械刺激的反应

Murciano, Nicoletta; Rotordam, Maria Giustina; Becker, Nadine; Ludlow, Melanie J; Parsonage, Gregory; Darras, Alexis; Kaestner, Lars; Beech, David J; George, Michael; Fertig, Niels; Rapedius, Markus; Brüggemann, Andrea

A modern automated patch-clamp approach for high throughput electrophysiology recordings in native cardiomyocytes.

一种用于在天然心肌细胞中进行高通量电生理记录的现代自动化膜片钳方法

Seibertz Fitzwilliam, Rapedius Markus, Fakuade Funsho E, Tomsits Philipp, Liutkute Aiste, Cyganek Lukas, Becker Nadine, Majumder Rupamanjari, Clauß Sebastian, Fertig Niels, Voigt Niels

There is no F in APC: Using physiological fluoride-free solutions for high throughput automated patch clamp experiments

APC 中不含氟:使用生理性无氟溶液进行高通量自动化膜片钳实验

Rapedius, Markus; Obergrussberger, Alison; Humphries, Edward S A; Scholz, Stephanie; Rinke-Weiss, Ilka; Goetze, Tom A; Brinkwirth, Nina; Rotordam, Maria Giustina; Strassmaier, Tim; Randolph, Aaron; Friis, Søren; Liutkute, Aiste; Seibertz, Fitzwilliam; Voigt, Niels; Fertig, Niels

Corrigendum to "A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm" [Toxicology and Applied Pharmacology volume 394C (2020) 114961]

对“评估 hERG 阻滞效力的系统策略及其在新的心脏安全范式中的意义”的更正[毒理学和应用药理学卷 394C (2020) 114961]

Ridder, Bradley J; Leishman, Derek J; Bridgland-Taylor, Matthew; Samieegohar, Mohammadreza; Han, Xiaomei; Wu, Wendy W; Randolph, Aaron; Tran, Phu; Sheng, Jiansong; Danker, Timm; Lindqvist, Anders; Konrad, Daniel; Hebeisen, Simon; Polonchuk, Liudmila; Gissinger, Evgenia; Renganathan, Muthukrishnan; Koci, Bryan; Wei, Haiyang; Fan, Jingsong; Levesque, Paul; Kwagh, Jae; Imredy, John; Zhai, Jin; Rogers, Marc; Humphries, Edward; Kirby, Robert; Stoelzle-Feix, Sonja; Brinkwirth, Nina; Rotordam, Maria Giustina; Becker, Nadine; Friis, Søren; Rapedius, Markus; Goetze, Tom A; Strassmaier, Tim; Okeyo, George; Kramer, James; Kuryshev, Yuri; Wu, Caiyun; Himmel, Herbert; Mirams, Gary R; Strauss, David G; Bardenet, Remi; Li, Zhihua

A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm.

评估 hERG 阻滞效力的系统策略及其在新心脏安全范式中的意义

Ridder Bradley J, Leishman Derek J, Bridgland-Taylor Matthew, Samieegohar Mohammadreza, Han Xiaomei, Wu Wendy W, Randolph Aaron, Tran Phu, Sheng Jiansong, Danker Timm, Lindqvist Anders, Konrad Daniel, Hebeisen Simon, Polonchuk Liudmila, Gissinger Evgenia, Renganathan Muthukrishnan, Koci Bryan, Wei Haiyang, Fan Jingsong, Levesque Paul, Kwagh Jae, Imredy John, Zhai Jin, Rogers Marc, Humphries Edward, Kirby Robert, Stoelzle-Feix Sonja, Brinkwirth Nina, Rotordam Maria Giustina, Becker Nadine, Friis Søren, Rapedius Markus, Goetze Tom A, Strassmaier Tim, Okeyo George, Kramer James, Kuryshev Yuri, Wu Caiyun, Himmel Herbert, Mirams Gary R, Strauss David G, Bardenet Rémi, Li Zhihua

A novel gain-of-function mutation of Piezo1 is functionally affirmed in red blood cells by high-throughput patch clamp

利用高通量膜片钳技术,在红细胞中证实了一种新型的Piezo1功能获得性突变具有功能活性。

Rotordam, Maria G; Fermo, Elisa; Becker, Nadine; Barcellini, Wilma; Brüggemann, Andrea; Fertig, Niels; Egée, Stéphane; Rapedius, Markus; Bianchi, Paola; Kaestner, Lars