AXL mediates resistance to PI3Kα inhibition by activating the EGFR/PKC/mTOR axis in head and neck and esophageal squamous cell carcinomas
AXL 通过激活头颈部和食管鳞状细胞癌中的 EGFR/PKC/mTOR 轴来介导对 PI3Kα 抑制的抵抗
期刊:Cancer Cell
影响因子:48.8
doi:10.1016/j.ccell.2015.03.010
Moshe Elkabets, Evangelos Pazarentzos, Dejan Juric, Qing Sheng, Raphael A Pelossof, Samuel Brook, Ana Oaknin Benzaken, Jordi Rodon, Natasha Morse, Jenny Jiacheng Yan, Manway Liu, Rita Das, Yan Chen, Angela Tam, Huiqin Wang, Jinsheng Liang, Joseph M Gurski, Darcy A Kerr, Rafael Rosell, Cristina Teixi
