日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Rational redesign of high-activity G-quadruplex DNAzyme through flanking and looping of nucleobases

通过核碱基侧翼和环化对高活性G-四链体DNA酶进行合理重新设计

Adeoye, Raphael I; Babbudas, Nikhildas; Birchenough, Matthew; Giuntini, Francesca; Olorunniji, Femi J

RNA G-Quadruplex RIBOTAC-Mediated Targeted Degradation of lncRNA TERRA.

RNA G-四链体RIBOTAC介导的lncRNA TERRA靶向降解。

Khaskia Elias, Dahatonde Dipak, Benhamou Raphael I

Druglike Molecular Degraders of the Oncogenic RNA-Binding Protein HuR.

致癌RNA结合蛋白HuR的类药物分子降解剂

Kassabri Liann, Benhamou Raphael I

Spermine Enhances the Peroxidase Activities of Multimeric Antiparallel G-quadruplex DNAzymes

亚精胺增强多聚体反平行G-四链体DNA酶的过氧化物酶活性

Adeoye, Raphael I; Ralebitso-Senior, Theresia K; Boddis, Amanda; Reid, Amanda J; Giuntini, Francesca; Fatokun, Amos A; Powell, Andrew K; Ihekwaba-Ndibe, Adaoha; Malomo, Sylvia O; Olorunniji, Femi J

Leveraging RIBOTAC technology: Fluorescent RNase L probes for live-cell imaging and function analysis

利用 RIBOTAC 技术:荧光 RNase L 探针用于活细胞成像和功能分析

Elias Khaskia, Raphael I Benhamou

Targeting MicroRNAs with Small Molecules

利用小分子靶向microRNA

Tadesse, Kisanet; Benhamou, Raphael I

Programming inactive RNA-binding small molecules into bioactive degraders

将无活性的 RNA 结合小分子编程为生物活性降解剂

Yuquan Tong #, Yeongju Lee #, Xiaohui Liu #, Jessica L Childs-Disney #, Blessy M Suresh, Raphael I Benhamou, Chunying Yang, Weimin Li, Matthew G Costales, Hafeez S Haniff, Sonja Sievers, Daniel Abegg, Tristan Wegner, Tiffany O Paulisch, Elizabeth Lekah, Maison Grefe, Gogce Crynen, Montina Van Meter,

Methods for the study of ribonuclease targeting chimeras (RiboTACs)

核糖核酸酶靶向嵌合体 (RiboTAC) 的研究方法

Noah A Springer, Samantha M Meyer, Amirhossein Taghavi, Raphael I Benhamou, Yuquan Tong, Jessica L Childs-Disney, Matthew D Disney

DNA-encoded library versus RNA-encoded library selection enables design of an oncogenic noncoding RNA inhibitor

DNA编码文库与RNA编码文库的筛选方法能够设计致癌性非编码RNA抑制剂。

Benhamou, Raphael I; Suresh, Blessy M; Tong, Yuquan; Cochrane, Wesley G; Cavett, Valerie; Vezina-Dawod, Simon; Abegg, Daniel; Childs-Disney, Jessica L; Adibekian, Alexander; Paegel, Brian M; Disney, Matthew D

Bioinformatic Searching for Optimal RNA Targets of Dimeric Compounds Informs Design of a MicroRNA-27a Inhibitor

利用生物信息学方法寻找二聚体化合物的最佳RNA靶点,为microRNA-27a抑制剂的设计提供信息。

Benhamou, Raphael I; Choudhary, Shruti; Lekah, Elizabeth; Tong, Yuquan; Disney, Matthew D