日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Islet cell stress induced by insulin-degrading enzyme deficiency promotes regeneration and protection from autoimmune diabetes

胰岛素降解酶缺乏引起的胰岛细胞应激促进再生并预防自身免疫性糖尿病

Shuaishuai Zhu, Emmanuelle Waeckel-Énée, Masaya Oshima, Anna Moser, Marie-Andrée Bessard, Abdelaziz Gdoura, Kevin Roger, Nina Mode, Joanna Lipecka, Ayse Yilmaz, Barbara Bertocci, Julien Diana, Benjamin Saintpierre, Ida Chiara Guerrera, Raphael Scharfmann, Stefania Francesconi, François-Xavier Mauvai

Human GLP1R variants affecting GLP1R cell surface expression are associated with impaired glucose control and increased adiposity

影响GLP1R细胞表面表达的人类GLP1R变异体与血糖控制受损和脂肪堆积增加有关。

Wenwen Gao ,Lei Liu ,Eunna Huh ,Florence Gbahou ,Erika Cecon ,Masaya Oshima ,Ludivine Houzé ,Panagiotis Katsonis ,Alan Hegron ,Zhiran Fan ,Guofei Hou ,Guillaume Charpentier ,Mathilde Boissel ,Mehdi Derhourhi ,Michel Marre ,Beverley Balkau ,Philippe Froguel ,Raphael Scharfmann ,Olivier Lichtarge ,Julie Dam ,Amélie Bonnefond ,Jianfeng Liu ,Ralf Jockers

Tryptophan metabolism promotes immune evasion in human pancreatic β cells

色氨酸代谢促进人胰岛β细胞的免疫逃逸。

Latif Rachdi ,Zhicheng Zhou ,Claire Berthault ,Chloe Lourenço ,Alexis Fouque ,Thomas Domet ,Mathieu Armanet ,Sylvaine You ,Mark Peakman ,Roberto Mallone ,Raphael Scharfmann

Characterization of the Secretome, Transcriptome, and Proteome of Human β Cell Line EndoC-βH1

人β细胞系EndoC-βH1的分泌组、转录组和蛋白质组特征分析

Maria Ryaboshapkina ,Kevin Saitoski ,Ghaith M Hamza ,Andrew F Jarnuczak ,Séverine Pechberty ,Claire Berthault ,Kaushik Sengupta ,Christina Rye Underwood ,Shalini Andersson ,Raphael Scharfmann

Proprotein convertase PCSK9 affects expression of key surface proteins in human pancreatic beta cells via intracellular and extracellular regulatory circuits

前蛋白转化酶PCSK9通过细胞内和细胞外调控回路影响人胰岛β细胞中关键表面蛋白的表达。

Kevin Saitoski ,Maria Ryaboshapkina ,Ghaith M Hamza ,Andrew F Jarnuczak ,Claire Berthault ,Françoise Carlotti ,Mathieu Armanet ,Kaushik Sengupta ,Christina Rye Underwood ,Shalini Andersson ,Isabelle Guillas ,Wilfried Le Goff ,Raphael Scharfmann

Glucose treatment of human pancreatic β-cells enhances translation of mRNAs involved in energetics and insulin secretion

葡萄糖治疗人类胰腺 β 细胞可增强与能量和胰岛素分泌有关的 mRNA 翻译

Albatoul Zakaria, Claire Berthault, Bertrand Cosson, Vincent Jung, Ida Chiara Guerrera, Latif Rachdi, Raphael Scharfmann

A surrogate of Roux-en-Y gastric bypass (the enterogastro anastomosis surgery) regulates multiple beta-cell pathways during resolution of diabetes in ob/ob mice

Roux-en-Y 胃旁路手术(肠胃吻合术)的替代方法可在 ob/ob 小鼠糖尿病消退过程中调节多种 β 细胞通路

Chloé Amouyal, Julien Castel, Claudiane Guay, Amélie Lacombe, Jessica Denom, Stéphanie Migrenne-Li, Christine Rouault, Florian Marquet, Eleni Georgiadou, Theodoros Stylianides, Serge Luquet, Hervé Le Stunff, Raphael Scharfmann, Karine Clément, Guy A Rutter, Olivier Taboureau, Christophe Magnan, Roma

Modeling human pancreatic beta cell dedifferentiation

人类胰腺β细胞去分化建模

Marc Diedisheim, Masaya Oshima, Olivier Albagli, Charlotte Wennberg Huldt, Ingela Ahlstedt, Maryam Clausen, Suraj Menon, Alexander Aivazidis, Anne-Christine Andreasson, William G Haynes, Piero Marchetti, Lorella Marselli, Mathieu Armanet, Fabrice Chimienti, Raphael Scharfmann

Virus-like infection induces human β cell dedifferentiation

病毒样感染诱导人类β细胞去分化

Masaya Oshima, Klaus-Peter Knoch, Marc Diedisheim, Antje Petzold, Pierre Cattan, Marco Bugliani, Piero Marchetti, Pratik Choudhary, Guo-Cai Huang, Stefan R Bornstein, Michele Solimena, Olivier Albagli-Curiel, Raphael Scharfmann

MondoA Is an Essential Glucose-Responsive Transcription Factor in Human Pancreatic β-Cells

MondoA 是人类胰腺 β 细胞中必需的葡萄糖反应转录因子

Paul Richards, Latif Rachdi, Masaya Oshima, Piero Marchetti, Marco Bugliani, Mathieu Armanet, Catherine Postic, Sandra Guilmeau, Raphael Scharfmann