日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Jagged1 regulates extracellular matrix deposition and remodeling in triple-negative breast cancer

Jagged1 调控三阴性乳腺癌中的细胞外基质沉积和重塑

Parikainen, Marjaana; Suwal, Ujjwal; Rappu, Pekka; Heino, Jyrki; Sahlgren, Cecilia M

C1s protects cutaneous squamous carcinoma cells from TRAIL-induced apoptosis

C1s保护皮肤鳞状细胞癌细胞免受TRAIL诱导的细胞凋亡

Salmela, Maria; Nissinen, Liisa; Rappu, Pekka; Viiklepp, Kristina; Ojalill, Marjaana; Heino, Jyrki; Riihilä, Pilvi; Kähäri, Veli-Matti

Embigin is involved in the regulation of early mouse kidney development.

Embigin参与调控小鼠早期肾脏发育。

Talvi Salli, Jokinen Johanna, Rappu Pekka, Leppäkoski Roni, Kurtzeborn Kristen, Rantakari Pia, Kuure Satu, Heino Jyrki

A One-Step Workflow for Size-Based Separation of Extracellular Vesicles With Integrated Surface Marker Detection.

基于尺寸的细胞外囊泡分离一步法工作流程及表面标志物检测。

Lippens Lien, Guilbert Niké, Van Dorpe Sofie, Deville Sarah, Boiy Robin, Roux Quentin, Lumen Nicolaas, Miinalainen Ilkka, Rappu Pekka, Vandecasteele Katrien, Denys Hannelore, De Geest Bruno, De Wever Olivier, Hendrix An

Dual-ligand PROTACS mediate superior target protein degradation in vitro and therapeutic efficacy in vivo

双配体PROTACS在体外可介导更优异的靶蛋白降解,并在体内展现出治疗效果。

Chen, Yong; Xia, Zihan; Suwal, Ujjwal; Rappu, Pekka; Heino, Jyrki; De Wever, Olivier; De Geest, Bruno G

Cancer-associated fibroblasts mediate resistance to neoadjuvant therapy in breast cancer

癌症相关成纤维细胞介导乳腺癌新辅助治疗的耐药性

Xia, Zihan; Vermeulen, Stephanie; Suwal, Ujjwal; Rappu, Pekka; Heino, Jyrki; De Vuyst, Felix; Dedeyne, Sandor; Hendrix, An; Denys, Hannelore; De Wever, Olivier

Embigin deficiency leads to delayed embryonic lung development and high neonatal mortality in mice

Embigin 缺乏导致小鼠胚胎肺发育延迟和新生儿死亡率高

Salli Talvi, Johanna Jokinen, Kalle Sipilä, Pekka Rappu, Fu-Ping Zhang, Matti Poutanen, Pia Rantakari, Jyrki Heino

Pelophen B is a non-taxoid binding microtubule-stabilizing agent with promising preclinical anticancer properties

Pelophen B 是一种非紫杉醇结合微管稳定剂,具有良好的临床前抗癌特性

Stephanie Vermeulen, Sam Ernst, Eva Blondeel, Zihan Xia, Pekka Rappu, Jyrki Heino, Sándor Dedeyne, Hannelore Denys, Gwen Sys, Stefanie Gijsels, Herman Depypere, Philippe Tummers, Wim Ceelen, Ligia Craciun, Pieter Demetter, Olivier Raes, An Hendrix, Johan Van der Eycken, Olivier De Wever1

Benchmarking blood collection tubes and processing intervals for extracellular vesicle performance metrics

对采血管和处理间隔进行基准测试,以确定细胞外囊泡的性能指标

Bert Dhondt, Cláudio Pinheiro, Edward Geeurickx, Joeri Tulkens, Glenn Vergauwen, Edwin Van Der Pol, Rienk Nieuwland, Anneleen Decock, Ilkka Miinalainen, Pekka Rappu, Gary Schroth, Scott Kuersten, Jo Vandesompele, Pieter Mestdagh, Nicolaas Lumen, Olivier De Wever, An Hendrix

Integrating automated liquid handling in the separation workflow of extracellular vesicles enhances specificity and reproducibility

在细胞外囊泡分离工作流程中整合自动化液体处理可提高特异性和可重复性

Sofie Van Dorpe, Lien Lippens, Robin Boiy, Cláudio Pinheiro, Glenn Vergauwen, Pekka Rappu, Ilkka Miinalainen, Philippe Tummers, Hannelore Denys, Olivier De Wever, An Hendrix