日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

AAV-mediated overexpression of CPT1B protects from cardiac hypertrophy and heart failure in a murine pressure overload model

在小鼠压力超负荷模型中,AAV介导的CPT1B过表达可保护心脏免受肥大和心力衰竭的损害。

Kliesow Remes, Anca; Ruf, Theresa; Zurashvili, Tinatin; Ding, Lin; Meyer-Jens, Moritz; Schwab, Dominic M; Hille, Susanne; Matzen, Andrea; Michalewski, Sabine; Kilian, Lucia; Shetty, Prithviraj Manohar Vijaya; Fuchs, Marie-Christin; Eden, Matthias; Gröne, Hermann-Josef; Rapti, Kleopatra; Jungmann, Andreas; Milting, Hendrik; Katus, Hugo A; Carrier, Lucie; Frank, Derk; Frey, Norbert; Müller, Oliver J

Membrane remodelling triggers maturation of excitation-contraction coupling in 3D-shaped human-induced pluripotent stem cell-derived cardiomyocytes

膜重塑触发三维形态的人诱导多能干细胞衍生心肌细胞兴奋-收缩耦联的成熟

Kermani, Fatemeh; Mosqueira, Matias; Peters, Kyra; Lemma, Enrico D; Rapti, Kleopatra; Grimm, Dirk; Bastmeyer, Martin; Laugsch, Magdalena; Hecker, Markus; Ullrich, Nina D

Induction of Hepatitis E Virus Anti-ORF3 Antibodies from Systemic Administration of a Muscle-Specific Adeno-Associated Virus (AAV) Vector

通过全身注射肌肉特异性腺相关病毒(AAV)载体诱导戊型肝炎病毒抗ORF3抗体

Maurer, Lars; El Andari, Jihad; Rapti, Kleopatra; Spreyer, Laura; Steinmann, Eike; Grimm, Dirk; Dao Thi, Viet Loan

Adeno-Associated Viruses (AAV) and Host Immunity - A Race Between the Hare and the Hedgehog

腺相关病毒(AAV)与宿主免疫——一场兔子与刺猬的赛跑

Rapti, Kleopatra; Grimm, Dirk

AAV-Mediated Expression of AP-1-Neutralizing RNA Decoy Oligonucleotides Attenuates Transplant Vasculopathy in Mouse Aortic Allografts

AAV介导的AP-1中和RNA诱饵寡核苷酸表达可减轻小鼠主动脉同种异体移植的移植血管病变

Remes, Anca; Franz, Maximilian; Mohr, Franziska; Weber, Antje; Rapti, Kleopatra; Jungmann, Andreas; Karck, Matthias; Hecker, Markus; Kallenbach, Klaus; Müller, Oliver J; Arif, Rawa; Wagner, Andreas H

Dominant negative Ras attenuates pathological ventricular remodeling in pressure overload cardiac hypertrophy.

显性负性 Ras 可减轻压力负荷过重引起的心脏肥大中的病理性心室重塑

Ramos-Kuri Manuel, Rapti Kleopatra, Mehel Hind, Zhang Shihong, Dhandapany Perundurai S, Liang Lifan, García-Carrancá Alejandro, Bobe Regis, Fischmeister Rodolphe, Adnot Serge, Lebeche Djamel, Hajjar Roger J, Lipskaia Larissa, Chemaly Elie R

Active inhibitor-1 maintains protein hyper-phosphorylation in aging hearts and halts remodeling in failing hearts

活性抑制剂-1维持衰老心脏中的蛋白质过度磷酸化,并阻止衰竭心脏的重塑。

Pritchard, Tracy J; Kawase, Yoshiaki; Haghighi, Kobra; Anjak, Ahmad; Cai, Wenfeng; Jiang, Min; Nicolaou, Persoulla; Pylar, George; Karakikes, Ioannis; Rapti, Kleopatra; Rubinstein, Jack; Hajjar, Roger J; Kranias, Evangelia G

Concomitant intravenous nitroglycerin with intracoronary delivery of AAV1.SERCA2a enhances gene transfer in porcine hearts

在猪心脏中,静脉注射硝酸甘油与冠状动脉内递送AAV1.SERCA2a同时进行,可增强基因转移。

Karakikes, Ioannis; Hadri, Lahouaria; Rapti, Kleopatra; Ladage, Dennis; Ishikawa, Kiyotake; Tilemann, Lisa; Yi, Geng-Hua; Morel, Charlotte; Gwathmey, Judith K; Zsebo, Krisztina; Weber, Thomas; Kawase, Yoshiaki; Hajjar, Roger J

Targeted gene therapy for the treatment of heart failure

靶向基因疗法治疗心力衰竭

Rapti, Kleopatra; Chaanine, Antoine H; Hajjar, Roger J

Aortic implantation of mesenchymal stem cells after aneurysm injury in a porcine model

猪模型中动脉瘤损伤后主动脉内移植间充质干细胞

Turnbull, Irene C; Hadri, Lahouaria; Rapti, Kleopatra; Sadek, Mikel; Liang, Lifan; Shin, Hyun J; Costa, Kevin D; Marin, Michael L; Hajjar, Roger J; Faries, Peter L