日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Inhibition of mucus secretion by niclosamide and benzbromarone in airways and intestine

氯硝柳胺和苯溴马隆抑制呼吸道和肠道黏液分泌

Jiraporn Ousingsawat, Raquel Centeio, Nicole Reyne, Alexandra McCarron, Patricia Cmielewski, Rainer Schreiber, Gabriella diStefano, Dorothee Römermann, Ursula Seidler, Martin Donnelley, Karl Kunzelmann

Niclosamide, but not ivermectin, inhibits anoctamin 1 and 6 and attenuates inflammation of the respiratory tract

氯硝柳胺可抑制阿诺克明 1 和 6,并减轻呼吸道炎症,而伊维菌素则不行

Jiraporn Ousingsawat, Raquel Centeio, Rainer Schreiber, Karl Kunzelmann

TMEM16A/F support exocytosis but do not inhibit Notch-mediated goblet cell metaplasia of BCi-NS1.1 human airway epithelium

TMEM16A/F 支持胞吐,但不抑制 Notch 介导的 BCi-NS1.1 人气道上皮杯状细胞化生

Raquel Centeio, Inês Cabrita, Rainer Schreiber, Karl Kunzelmann

KCNE1 does not shift TMEM16A from a Ca2+ dependent to a voltage dependent Cl- channel and is not expressed in renal proximal tubule

KCNE1 不会将 TMEM16A 从 Ca2+ 依赖性转变为电压依赖性 Cl- 通道,并且不在肾近端小管中表达

Khaoula Talbi, Jiraporn Ousingsawat, Raquel Centeio, Rainer Schreiber, Karl Kunzelmann

Expression of SLC26A9 in Airways and Its Potential Role in Asthma

SLC26A9 在气道中的表达及其在哮喘中的潜在作用

Jiraporn Ousingsawat, Raquel Centeio, Rainer Schreiber, Karl Kunzelmann

Airway Delivery of Hydrogel-Encapsulated Niclosamide for the Treatment of Inflammatory Airway Disease

水凝胶包裹的氯硝柳胺通过气道输送治疗炎症性气道疾病

Jiraporn Ousingsawat, Raquel Centeio, Inês Cabrita, Khaoula Talbi, Oliver Zimmer, Moritz Graf, Achim Göpferich, Rainer Schreiber, Karl Kunzelmann

Drug Repurposing for Cystic Fibrosis: Identification of Drugs That Induce CFTR-Independent Fluid Secretion in Nasal Organoids

囊性纤维化的药物再利用:鉴定诱导鼻腔类器官中 CFTR 非依赖性液体分泌的药物

Lisa W Rodenburg, Livia Delpiano, Violeta Railean, Raquel Centeio, Madalena C Pinto, Shannon M A Smits, Isabelle S van der Windt, Casper F J van Hugten, Sam F B van Beuningen, Remco N P Rodenburg, Cornelis K van der Ent, Margarida D Amaral, Karl Kunzelmann, Michael A Gray, Jeffrey M Beekman, Gimano

Mucus Release and Airway Constriction by TMEM16A May Worsen Pathology in Inflammatory Lung Disease

TMEM16A 引起的粘液释放和气道收缩可能会加重炎症性肺病的病理

Raquel Centeio, Jiraporn Ousingsawat, Inês Cabrita, Rainer Schreiber, Khaoula Talbi, Roberta Benedetto, Tereza Doušová, Eric K Verbeken, Kris De Boeck, Isaac Cohen, Karl Kunzelmann

CLCA1 Regulates Airway Mucus Production and Ion Secretion Through TMEM16A

CLCA1通过TMEM16A调节气道粘液产生和离子分泌

Raquel Centeio, Jiraporn Ousingsawat, Rainer Schreiber, Karl Kunzelmann

Calmodulin-Dependent Regulation of Overexpressed but Not Endogenous TMEM16A Expressed in Airway Epithelial Cells

钙调蛋白依赖性调节气道上皮细胞中过表达而非内源性的 TMEM16A

Khaoula Talbi, Jiraporn Ousingsawat, Raquel Centeio, Rainer Schreiber, Karl Kunzelmann