Physical presence of nor-binaltorphimine in mouse brain over 21 days after a single administration corresponds to its long-lasting antagonistic effect on κ-opioid receptors
单次给药后21天内,小鼠脑内仍能检测到nor-binaltorphimine的物理存在,这与其对κ-阿片受体的持久拮抗作用相符。
期刊:Journal of Pharmacology and Experimental Therapeutics
影响因子:3.8
doi:10.1124/jpet.113.206086
Patkar, Kshitij A; Wu, Jinhua; Ganno, Michelle L; Singh, Harminder D; Ross, Nicolette C; Rasakham, Khampaseuth; Toll, Lawrence; McLaughlin, Jay P