NLRP3 inflammasome-driven hemophagocytic lymphohistiocytosis occurs independent of IL-1β and IL-18 and is targetable by BET inhibitors.
NLRP3炎症小体驱动的噬血细胞性淋巴组织细胞增生症的发生与IL-1β和IL-18无关，并且是BET抑制剂的靶点
期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.adv0079
Shojaee Farzaneh, Azadian Esmaeel, Wong Min Xian, Ma Xiuquan, Rickard James, Pang Jiyi, Hall Catherine, Kueh Andrew J, Masters Seth L, Rioja Inmaculada, Prinjha Rab K, Doerflinger Marcel, Lawlor Kate E, Rashidi Maryam, Vince James E
