Genome rearrangements induced by the stimulation of end-joining of DNA double strand breaks through multiple phosphorylation of MRE11 by the kinase PKB/AKT1.
通过激酶 PKB/AKT1 对 MRE11 进行多次磷酸化,刺激 DNA 双链断裂末端连接,从而诱导基因组重排
期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkaf468
Guirouilh-Barbat Josée, Boueya Iman Litchy, Gelot Camille, Pennarun Gaëlle, Granotier-Beckers Christine, Dardillac Elodie, Yu Wei, Lescale Chloé, Rass Emilie, Ariste Olivier, Siaud Nicolas, Renouf Benjamin, Millet Armel, Puget Nadine, Bertrand Pascale, de la Grange Pierre, Brunet Erika, Deriano Ludovic, Lopez Bernard S