日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Nitric oxide promotes cysteine N-degron proteolysis through control of oxygen availability.

一氧化氮通过控制氧气供应来促进半胱氨酸 N-降解子的蛋白水解

Kim Haeun, Tian Ya-Min, Ratcliffe Peter J, Keeley Thomas P

Making sense of oxygen sensing

理解氧气传感

Ratcliffe, Peter J; Keeley, Thomas P

Hypoxia-Inducible Factor 2α: at the Interface between Oxygen Sensing Systems in Physiology and Pathology

缺氧诱导因子2α:生理和病理氧感知系统的交汇点

Bishop, Tammie; Ratcliffe, Peter J

Deficiency of factor-inhibiting HIF creates a tumor-promoting immune microenvironment

抑制因子HIF的缺乏会造成促进肿瘤生长的免疫微环境。

Ma, Jingyi; Al Moussawi, Khatoun; Lou, Hantao; Chan, Hok Fung; Wang, Yihua; Chadwick, Joseph; Phetsouphanh, Chansavath; Slee, Elizabeth A; Zhong, Shan; Leissing, Thomas M; Roth, Andrew; Qin, Xiao; Chen, Shuo; Yin, Jie; Ratnayaka, Indrika; Hu, Yang; Louphrasitthiphol, Pakavarin; Taylor, Lewis; Bettencourt, Paulo J G; Muers, Mary; Greaves, David R; McShane, Helen; Goldin, Robert; Soilleux, Elizabeth J; Coleman, Mathew L; Ratcliffe, Peter J; Lu, Xin

Author Correction: Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation

作者更正:缺氧会影响肺损伤中的免疫环境,并促进炎症持续存在。

Mirchandani, Ananda S; Jenkins, Stephen J; Bain, Calum C; Sanchez-Garcia, Manuel A; Lawson, Hannah; Coelho, Patricia; Murphy, Fiona; Griffith, David M; Zhang, Ailiang; Morrison, Tyler; Ly, Tony; Arienti, Simone; Sadiku, Pranvera; Watts, Emily R; Dickinson, Rebecca S; Reyes, Leila; Cooper, George; Clark, Sarah; Lewis, David; Kelly, Van; Spanos, Christos; Musgrave, Kathryn M; Delaney, Liam; Harper, Isla; Scott, Jonathan; Parkinson, Nicholas J; Rostron, Anthony J; Baillie, J Kenneth; Clohisey, Sara; Pridans, Clare; Campana, Lara; Lewis, Philip Starkey; Simpson, A John; Dockrell, David H; Schwarze, Jürgen; Hirani, Nikhil; Ratcliffe, Peter J; Pugh, Christopher W; Kranc, Kamil; Forbes, Stuart J; Whyte, Moira K B; Walmsley, Sarah R

A global view of the aspiring physician-scientist

从全球视角看有志成为医生科学家的年轻人

Williams, Christopher S; Rathmell, W Kimryn; Carethers, John M; Harper, Diane M; Lo, Y M Dennis; Ratcliffe, Peter J; Zaidi, Mone

Harveian Oration 2020: Elucidation of molecular oxygen sensing mechanisms in human cells: implications for medicine

2020年哈维演讲:阐明人类细胞中分子氧感知机制:对医学的启示

Ratcliffe, Peter J

Precisely Tuned Inhibition of HIF Prolyl Hydroxylases Is Key for Cardioprotection After Ischemia

精确调控HIF脯氨酰羟化酶的抑制是缺血后心脏保护的关键

Jatho, Aline; Zieseniss, Anke; Brechtel-Curth, Katja; Yamamoto, Atsushi; Coleman, Mathew L; Vergel Leon, Ana M; Biggs, Daniel; Davies, Ben; Pugh, Chris W; Ratcliffe, Peter J; Katschinski, Dörthe M

Structure-Activity Relationship and Crystallographic Studies on 4-Hydroxypyrimidine HIF Prolyl Hydroxylase Domain Inhibitors

4-羟基嘧啶类HIF脯氨酰羟化酶结构域抑制剂的构效关系及晶体学研究

Holt-Martyn, James P; Chowdhury, Rasheduzzaman; Tumber, Anthony; Yeh, Tzu-Lan; Abboud, Martine I; Lippl, Kerstin; Lohans, Christopher T; Langley, Gareth W; Figg, William Jr; McDonough, Michael A; Pugh, Christopher W; Ratcliffe, Peter J; Schofield, Christopher J

Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants

保守的N端半胱氨酸双加氧酶在动植物中传递对缺氧的反应。

Masson, Norma; Keeley, Thomas P; Giuntoli, Beatrice; White, Mark D; Puerta, Mikel Lavilla; Perata, Pierdomenico; Hopkinson, Richard J; Flashman, Emily; Licausi, Francesco; Ratcliffe, Peter J