日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Statin Use Is Associated With Protection Against Acute Cholangitis in Patients With Primary Sclerosing Cholangitis: A Multicenter Retrospective Cohort Study

他汀类药物的使用与原发性硬化性胆管炎患者预防急性胆管炎相关:一项多中心回顾性队列研究

Kulkarni, Chiraag; Cholankeril, George; Fardeen, Touran; Rathkey, Joseph; Khan, Samir; Murag, Soumya; Lerrigo, Robert; Kamal, Ahmad; Mannalithara, Ajitha; Jalal, Prasun; Ahmed, Aijaz; Vierling, John; Goel, Aparna; Sinha, Sidhartha R

Sensitivity of Mesothelioma Cells to PARP Inhibitors Is Not Dependent on BAP1 but Is Enhanced by Temozolomide in Cells With High-Schlafen 11 and Low-O6-methylguanine-DNA Methyltransferase Expression

间皮瘤细胞对 PARP 抑制剂的敏感性不依赖于 BAP1,但在高 Schlafen 11 和低 O6-甲基鸟嘌呤-DNA 甲基转移酶表达的细胞中,替莫唑胺可增强其敏感性

Daniel Rathkey, Manakamana Khanal, Junko Murai, Jingli Zhang, Manjistha Sengupta, Qun Jiang, Betsy Morrow, Christine N Evans, Raj Chari, Patricia Fetsch, Hye-Jung Chung, Liqiang Xi, Mark Roth, Armando Filie, Mark Raffeld, Anish Thomas, Yves Pommier, Raffit Hassan

Enhanced efficacy of mesothelin-targeted immunotoxin LMB-100 and anti-PD-1 antibody in patients with mesothelioma and mouse tumor models

间皮素靶向免疫毒素 LMB-100 和抗 PD-1 抗体对间皮瘤患者和小鼠肿瘤模型的增强疗效

Qun Jiang, Azam Ghafoor, Idrees Mian, Daniel Rathkey, Anish Thomas, Christine Alewine, Manjistha Sengupta, Mark A Ahlman, Jingli Zhang, Betsy Morrow, Seth M Steinberg, Ira Pastan, Raffit Hassan

N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis

N-GSDMD 运输至中性粒细胞器可促进 IL-1β 释放,而不依赖于质膜孔和细胞焦亡

Mausita Karmakar, Martin Minns, Elyse N Greenberg, Jose Diaz-Aponte, Kersi Pestonjamasp, Jennifer L Johnson, Joseph K Rathkey, Derek W Abbott, Kun Wang, Feng Shao, Sergio D Catz, George R Dubyak, Eric Pearlman

Human polymorphisms in GSDMD alter the inflammatory response

GSDMD 中的人类多态性会改变炎症反应

Joseph K Rathkey, Tsan S Xiao, Derek W Abbott

Chemical disruption of the pyroptotic pore-forming protein gasdermin D inhibits inflammatory cell death and sepsis

焦亡成孔蛋白 gasdermin D 的化学破坏可抑制炎症细胞死亡和脓毒症

Joseph K Rathkey, Junjie Zhao, Zhonghua Liu, Yinghua Chen, Jie Yang, Hannah C Kondolf, Bryan L Benson, Steven M Chirieleison, Alex Y Huang, George R Dubyak, Tsan S Xiao, Xiaoxia Li, Derek W Abbott

Unique BIR domain sets determine inhibitor of apoptosis protein-driven cell death and NOD2 complex signal specificity

独特的BIR结构域集合决定了凋亡抑制蛋白驱动的细胞死亡和NOD2复合物的信号特异性

Chirieleison, Steven M; Rathkey, Joseph K; Abbott, Derek W

Structures of the Gasdermin D C-Terminal Domains Reveal Mechanisms of Autoinhibition

Gasdermin D C 端结构域的结构揭示了自身抑制的机制

Zhonghua Liu, Chuanping Wang, Joseph K Rathkey, Jie Yang, George R Dubyak, Derek W Abbott, Tsan Sam Xiao

Neurocognitive, Autonomic, and Mood Effects of Adderall: A Pilot Study of Healthy College Students

阿德拉对神经认知、自主神经和情绪的影响:一项针对健康大学生的初步研究

Weyandt, Lisa L; White, Tara L; Gudmundsdottir, Bergljot Gyda; Nitenson, Adam Z; Rathkey, Emma S; De Leon, Kelvin A; Bjorn, Stephanie A

Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor

炎症性胱天蛋白酶识别 Gasdermin D 的机制及其被 Gasdermin D 衍生肽抑制剂抑制

Jie Yang, Zhonghua Liu, Chuanping Wang, Rui Yang, Joseph K Rathkey, Otis W Pinkard, Wuxian Shi, Yinghua Chen, George R Dubyak, Derek W Abbott, Tsan Sam Xiao