日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Design, Synthesis, and Biological Evaluation of Novel Acetylcholinesterase and β-Secretase 1 Inhibitors

新型乙酰胆碱酯酶和β-分泌酶1抑制剂的设计、合成及生物学评价

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms27021008
Drozdowska, Danuta; Pawelski, Damian; Wróbel-Tałałaj, Agnieszka; Plonska-Brzezinska, Marta; Kolesinska, Beata; Lazny, Ryszard; Seroka, Barbara; Parzych, Cezary; Ratkiewicz, Artur
发表日期：2026
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Substituent and Ring-Number Effects on the Kinetics of PAH + OH Reactions: A QSAR-DOE Approach with Tunneling Corrections

取代基和环数对PAH + OH反应动力学的影响：基于隧道效应校正的QSAR-DOE方法

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules31020265
Parzych, Cezary; Baradyn, Maciej; Ratkiewicz, Artur
发表日期：2026
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Rational design, synthesis, and molecular modelling insights of dual DNA binders/DHFR inhibitors bearing arylidene-hydrazinyl-1,3-thiazole scaffold with apoptotic and anti-migratory potential in breast MCF-7 cancer cells.

对具有亚芳基肼基-1,3-噻唑骨架的双重DNA结合剂/DHFR抑制剂进行合理设计、合成和分子建模，以研究其在乳腺癌MCF-7细胞中的凋亡和抗迁移潜力

期刊:Journal of Enzyme Inhibition and Medicinal Chemistry
影响因子:5.4
doi:10.1080/14756366.2025.2468353
El-Wakil Marwa H, Ghazala Rasha A, El-Dershaby Hadeel A, Drozdowska Danuta, Wróbel-Tałałaj Agnieszka, Parzych Cezary, Ratkiewicz Artur, Kolesińska Beata, Abd El-Razik Heba A, Soliman Farid S G
细胞生物学
凋亡
发表日期：2025
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Repurposed Arylidene-hydrazinyl-1,3-thiazoles as Multitarget Anti-Alzheimer's Agents via Combined Computational and Experimental Studies

通过计算和实验相结合的研究，将亚芳基肼基-1,3-噻唑类化合物重新用于多靶点抗阿尔茨海默病治疗

期刊:ACS Omega
影响因子:4.3
doi:10.1021/acsomega.5c08737
Drozdowska, Danuta; Ratkiewicz, Artur; Wróbel-Tałałaj, Agnieszka; Parzych, Cezary; El-Dershaby, Hadeel A; Abd El-Razik, Heba A; Soliman, Farid S G; El-Wakil, Marwa H
阿尔茨海默症
发表日期：2025
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Benzamide Trimethoprim Derivatives as Human Dihydrofolate Reductase Inhibitors-Molecular Modeling and In Vitro Activity Study

苯甲酰胺类甲氧苄啶衍生物作为人二氢叶酸还原酶抑制剂——分子建模和体外活性研究

期刊:Biomedicines
影响因子:3.9
doi:10.3390/biomedicines12051079
Drozdowska, Danuta; Wróbel-Tałałaj, Agnieszka; Parzych, Cezary; Ratkiewicz, Artur
Human
发表日期：2024
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s-Triazine Derivatives Functionalized with Alkylating 2-Chloroethylamine Fragments as Promising Antimicrobial Agents: Inhibition of Bacterial DNA Gyrases, Molecular Docking Studies, and Antibacterial and Antifungal Activity

以烷基化2-氯乙胺片段功能化的s-三嗪衍生物作为有前景的抗菌剂：细菌DNA旋转酶抑制、分子对接研究以及抗菌和抗真菌活性

期刊:Pharmaceuticals
影响因子:4.8
doi:10.3390/ph16091248
Maliszewski, Dawid; Demirel, Rasime; Wróbel, Agnieszka; Baradyn, Maciej; Ratkiewicz, Artur; Drozdowska, Danuta
微生物学
发表日期：2023
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Synthesis, Biological Activity, and Molecular Dynamics Study of Novel Series of a Trimethoprim Analogs as Multi-Targeted Compounds: Dihydrofolate Reductase (DHFR) Inhibitors and DNA-Binding Agents

新型甲氧苄啶类似物系列作为多靶点化合物的合成、生物活性和分子动力学研究：二氢叶酸还原酶（DHFR）抑制剂和DNA结合剂

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms22073685
Wróbel, Agnieszka; Baradyn, Maciej; Ratkiewicz, Artur; Drozdowska, Danuta
发表日期：2021
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On-The-Fly Kinetics of the Hydrogen Abstraction by Hydroperoxyl Radical: An Application of the Reaction Class Transition State Theory

氢过氧自由基夺氢反应的动态动力学研究：反应类过渡态理论的应用

期刊:Frontiers in Chemistry
影响因子:4.2
doi:10.3389/fchem.2021.806873
Baradyn, Maciej; Ratkiewicz, Artur
发表日期：2021
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Thiamine and selected thiamine antivitamins - biological activity and methods of synthesis

硫胺素及其部分抗维生素——生物活性及合成方法

期刊:Bioscience Reports
影响因子:4.7
doi:10.1042/BSR20171148
Tylicki, Adam; Łotowski, Zenon; Siemieniuk, Magdalena; Ratkiewicz, Artur
发表日期：2018
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