NOTCH localizes to mitochondria through the TBC1D15-FIS1 interaction and is stabilized via blockade of E3 ligase and CDK8 recruitment to reprogram tumor-initiating cells
NOTCH 通过 TBC1D15-FIS1 相互作用定位到线粒体，并通过阻断 E3 连接酶和 CDK8 募集来稳定，从而重新编程肿瘤起始细胞
期刊:Experimental and Molecular Medicine
影响因子:9.5
doi:10.1038/s12276-024-01174-6
Hye Yeon Choi #, Yicheng Zhu #, Xuyao Zhao, Simran Mehta, Juan Carlos Hernandez, Jae-Jin Lee, Yi Kou, Risa Machida, Mauro Giacca, Giannino Del Sal, Ratna Ray, Hyungjin Eoh, Stanley M Tahara, Lin Chen, Hidekazu Tsukamoto, Keigo Machida
