日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Multi-State Structural Genomics Enables Large-Scale, Mechanistic, and Context-Specific Classification of ABCC6 Genetic Variants Implicated in Calcification Diseases

多状态结构基因组学能够对与钙化疾病相关的ABCC6基因变异进行大规模、机制性和情境特异性分类

Wagenknecht, Jessica B; Haque, Neshatul; Jorge, Salomao D; Ratnasinghe, Brian D; Urrutia, Raul; Gahl, William A; Ziegler, Shira G; Zimmermann, Michael T

A Multi-State Structural Genomics Approach Enables Large-Scale, Mechanistic, and Context-Specific Classification of ABCC6 Genetic Variants Implicated in Calcification Diseases

多状态结构基因组学方法能够对与钙化疾病相关的ABCC6基因变异进行大规模、机制性和情境特异性分类

Wagenknecht, Jessica B; Haque, Neshatul; Jorge, Salomao D; Ratnasinghe, Brian D; Urrutia, Raul; Gahl, William A; Ziegler, Shira G; Zimmermann, Michael T

Systematic analysis of the relationship between fold-dependent flexibility and artificial intelligence protein structure prediction

系统分析折叠依赖性柔性与人工智能蛋白质结构预测之间的关系

Haque, Neshatul; Wagenknecht, Jessica B; Ratnasinghe, Brian D; Zimmermann, Michael T

Beyond structural bioinformatics for genomics with dynamics characterization of an expanded KRAS mutational landscape

超越基因组学的结构生物信息学,动态表征扩展的 KRAS 突变景观

Brian D Ratnasinghe, Neshatul Haque, Jessica B Wagenknecht, Davin R Jensen, Guadalupe K Valdivia Esparza, Elise N Leverence, Thiago Milech De Assuncao, Angela J Mathison, Gwen Lomberk, Brian C Smith, Brian F Volkman, Raul Urrutia, Michael T Zimmermann

RAG genomic variation causes autoimmune diseases through specific structure-based mechanisms of enzyme dysregulation

RAG基因组变异通过特定的基于结构的酶失调机制导致自身免疫性疾病。

Haque, Neshatul; Kawai, Tomoki; Ratnasinghe, Brian D; Wagenknecht, Jessica B; Urrutia, Raul; Notarangelo, Luigi D; Zimmermann, Michael T

Beyond Structural Bioinformatics for Genomics with Dynamics Characterization of an Expanded KRAS Mutational Landscape

超越结构生物信息学,通过动态表征扩展的KRAS突变图谱,探索基因组学的新途径

Ratnasinghe, Brian D; Haque, Neshatul; Wagenknecht, Jessica B; Jensen, Davin R; Esparza, Guadalupe V; Leverence, Elise N; De Assuncao, Thiago Milech; Mathison, Angela J; Lomberk, Gwen; Smith, Brian C; Volkman, Brian F; Urrutia, Raul; Zimmermann, Michael T

Ion Binding Properties and Dynamics of the bcl-2 G-Quadruplex Using a Polarizable Force Field

利用可极化力场研究bcl-2 G-四链体的离子结合特性和动力学

Ratnasinghe, Brian D; Salsbury, Alexa M; Lemkul, Justin A

Community acquired Panton-Valentine Leukocidin (PVL) positive Methicilin Resistant Staphylococcal aureus cerebral abscess in an 11-month old boy: a case study

一名11个月大的男婴发生社区获得性Panton-Valentine白细胞毒素(PVL)阳性耐甲氧西林金黄色葡萄球菌脑脓肿:病例报告

Mutale, Wilbroad; Sahay, Keya M; Hartley, John; Thompson, Dominic; Ratnasinghe, Didi; Hudson, Lee; Hulse, Eleanor; Fellows, Greg

A prospective study of polymorphisms of DNA repair genes XRCC1, XPD23 and APE/ref-1 and risk of stroke in Linxian, China

中国林县DNA修复基因XRCC1、XPD23和APE/ref-1多态性与卒中风险的前瞻性研究

Mahabir, Somdat; Abnet, Christian C; Qiao, You-Lin; Ratnasinghe, Luke D; Dawsey, Sanford M; Dong, Zhi-Wei; Taylor, Philip R; Mark, Steven D

Decision forest analysis of 61 single nucleotide polymorphisms in a case-control study of esophageal cancer; a novel method

利用决策森林分析食管癌病例对照研究中的61个单核苷酸多态性;一种新方法

Xie, Qian; Ratnasinghe, Luke D; Hong, Huixiao; Perkins, Roger; Tang, Ze-Zhong; Hu, Nan; Taylor, Philip R; Tong, Weida