日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Challenges of non-clinical safety testing for biologics: A Report of the 9th BioSafe European Annual General Membership Meeting

生物制品非临床安全性测试的挑战:第九届欧洲生物安全协会年度会员大会报告

Kissner, Thomas; Blaich, Guenter; Baumann, Andreas; Kronenberg, Sven; Hey, Adam; Kiessling, Andrea; Schmitt, Petra M; Driessen, Wouter; Carrez, Chantal; Kramer, Daniel; Fretland, Jennifer; Richter, Wolfgang F; Paehler, Tobias; Hopfer, Ulrike; Rattel, Benno

AMG 701 induces cytotoxicity of multiple myeloma cells and depletes plasma cells in cynomolgus monkeys

AMG 701 诱导多发性骨髓瘤细胞的细胞毒性并消耗猕猴的浆细胞

Rebecca L Goldstein, Ana Goyos, Chi-Ming Li, Petra Deegen, Pamela Bogner, Alexander Sternjak, Oliver Thomas, Matthias Klinger, Joachim Wahl, Matthias Friedrich, Benno Rattel, Edwin Lamas, Xiaoshan Min, Athena Sudom, Mozhgan Farshbaf, Angela Coxon, Mercedesz Balazs, Tara Arvedson

A novel BCMA/CD3 bispecific T-cell engager for the treatment of multiple myeloma induces selective lysis in vitro and in vivo

用于治疗多发性骨髓瘤的新型 BCMA/CD3 双特异性 T 细胞接合剂可在体内和体外诱导选择性裂解

S Hipp, Y-T Tai, D Blanset, P Deegen, J Wahl, O Thomas, B Rattel, P J Adam, K C Anderson, M Friedrich

Clinical safety and pharmacological profile of the HLA-DR antibody 1D09C3 in patients with B cell chronic lymphocytic leukemia and lymphoma: results from a phase I study

HLA-DR抗体1D09C3在B细胞慢性淋巴细胞白血病和淋巴瘤患者中的临床安全性和药理学特征:一项I期研究的结果

Schweighofer, Carmen D; Tuchscherer, Armin; Sperka, Sabine; Meyer, Thorsten; Rattel, Benno; Stein, Sandra; Ismail, Semra; Elter, Thomas; Staib, Peter; Reiser, Marcel; Hallek, Michael

T cell-engaging BiTE antibodies specific for EGFR potently eliminate KRAS- and BRAF-mutated colorectal cancer cells

针对 EGFR 的 T 细胞结合 BiTE 抗体可有效清除 KRAS 和 BRAF 突变的结直肠癌细胞。

Lutterbuese, Ralf; Raum, Tobias; Kischel, Roman; Hoffmann, Patrick; Mangold, Susanne; Rattel, Benno; Friedrich, Matthias; Thomas, Oliver; Lorenczewski, Grit; Rau, Doris; Schaller, Evelyne; Herrmann, Ines; Wolf, Andreas; Urbig, Thomas; Baeuerle, Patrick A; Kufer, Peter