日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

ATPS-82: PROBING THE TUMORIGENIC PROPERTIES OF TWO PORE POTASSIUM CHANNELS USING INHIBITORY KCNK9 mAbs

ATPS-82:利用抑制性KCNK9单克隆抗体探测两种孔钾通道的致瘤特性

Bading, James R; Hörling, Magnus; Williams, Lawrence E; Colcher, David; Raubitschek, Andrew; Strand, Sven E; Sun, Han; Luo, Liqun; Lal, Bachchu; Ma, Xinrong; Chen, Lieping; Fulton, Amy; Leahy, Daniel; Laterra, John; Li, Min

TLR9-mediated siRNA delivery for targeting of normal and malignant human hematopoietic cells in vivo

利用TLR9介导的siRNA递送靶向体内正常和恶性人造血细胞

Zhang, Qifang; Hossain, Dewan Md Sakib; Nechaev, Sergey; Kozlowska, Anna; Zhang, Wang; Liu, Yong; Kowolik, Claudia M; Swiderski, Piotr; Rossi, John J; Forman, Stephen; Pal, Sumanta; Bhatia, Ravi; Raubitschek, Andrew; Yu, Hua; Kortylewski, Marcin

Intracellular processing of immunostimulatory CpG-siRNA: Toll-like receptor 9 facilitates siRNA dicing and endosomal escape

免疫刺激性 CpG-siRNA 的细胞内加工:Toll 样受体 9 促进 siRNA 的切割和内体逃逸

Nechaev, Sergey; Gao, Chan; Moreira, Dayson; Swiderski, Piotr; Jozwiak, Agnieszka; Kowolik, Claudia M; Zhou, Jiehua; Armstrong, Brian; Raubitschek, Andrew; Rossi, John J; Kortylewski, Marcin

CD20-specific adoptive immunotherapy for lymphoma using a chimeric antigen receptor with both CD28 and 4-1BB domains: pilot clinical trial results.

使用具有 CD28 和 4-1BB 结构域的嵌合抗原受体进行 CD20 特异性过继免疫疗法治疗淋巴瘤:初步临床试验结果

Till Brian G, Jensen Michael C, Wang Jinjuan, Qian Xiaojun, Gopal Ajay K, Maloney David G, Lindgren Catherine G, Lin Yukang, Pagel John M, Budde Lihua E, Raubitschek Andrew, Forman Stephen J, Greenberg Philip D, Riddell Stanley R, Press Oliver W

Site-specific conjugation of monodispersed DOTA-PEGn to a thiolated diabody reveals the effect of increasing peg size on kidney clearance and tumor uptake with improved 64-copper PET imaging

将单分散的DOTA-PEGn与硫醇化双抗体进行位点特异性偶联,揭示了增大聚乙二醇(PEGn)尺寸对肾脏清除率和肿瘤摄取的影响,并改善了64铜PET成像效果。

Li, Lin; Crow, Desiree; Turatti, Fabio; Bading, James R; Anderson, Anne-Line; Poku, Erasmus; Yazaki, Paul J; Carmichael, Jenny; Leong, David; Wheatcroft, David; Raubitschek, Andrew A; Hudson, Peter J; Colcher, David; Shively, John E

ImmunoPET imaging of B-cell lymphoma using 124I-anti-CD20 scFv dimers (diabodies)

利用 124I-抗 CD20 scFv 二聚体(双抗体)进行 B 细胞淋巴瘤的免疫 PET 成像

Olafsen, Tove; Sirk, Shannon J; Betting, David J; Kenanova, Vania E; Bauer, Karl B; Ladno, Waldemar; Raubitschek, Andrew A; Timmerman, John M; Wu, Anna M

Monodispersed DOTA-PEG-conjugated anti-TAG-72 diabody has low kidney uptake and high tumor-to-blood ratios resulting in improved 64Cu PET

单分散的DOTA-PEG偶联抗TAG-72双抗体具有肾脏摄取低、肿瘤/血液比高的特点,从而改善了64Cu PET显像效果。

Li, Lin; Turatti, Fabio; Crow, Desiree; Bading, James R; Anderson, Anne-Line; Poku, Erasmus; Yazaki, Paul J; Williams, Lawrence E; Tamvakis, Debra; Sanders, Paul; Leong, David; Raubitschek, Andrew; Hudson, Peter J; Colcher, David; Shively, John E

A phase I study of a combination of yttrium-90-labeled anti-carcinoembryonic antigen (CEA) antibody and gemcitabine in patients with CEA-producing advanced malignancies

一项针对产生癌胚抗原 (CEA) 的晚期恶性肿瘤患者的 I 期研究,评估钇-90 标记的抗癌胚抗原 (CEA) 抗体与吉西他滨联合治疗的疗效。

Shibata, Stephen; Raubitschek, Andrew; Leong, Lucille; Koczywas, Marianna; Williams, Lawrence; Zhan, Jiping; Wong, Jeffrey Y C

Recombinant anti-CD20 antibody fragments for small-animal PET imaging of B-cell lymphomas

用于小动物B细胞淋巴瘤PET成像的重组抗CD20抗体片段

Olafsen, Tove; Betting, David; Kenanova, Vania E; Salazar, Felix B; Clarke, Pat; Said, Jonathan; Raubitschek, Andrew A; Timmerman, John M; Wu, Anna M

Imaging immune response in vivo: cytolytic action of genetically altered T cells directed to glioblastoma multiforme

体内免疫反应成像:针对多形性胶质母细胞瘤的基因改造T细胞的细胞溶解作用

Lazovic, Jelena; Jensen, Michael C; Ferkassian, Evette; Aguilar, Brenda; Raubitschek, Andrew; Jacobs, Russell E