日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Enteric tuft cell inflammasome activation drives NKp46+ILC3 IL22 via PGD2 and inhibits Salmonella.

肠道簇状细胞炎症小体激活通过 PGD2 驱动 NKp46+ILC3 IL22 并抑制沙门氏菌

Churchill Madeline J, Pandeya Ankit, Bauer Renate, Christopher Tighe, Krug Stefanie, Honodel Roslyn, Smita Shuchi, Warner Lindsey, Mooney Bridget M, Gibson Alexis R, Mitchell Patrick S, Tait Wojno Elia D, Rauch Isabella

Immunostimulatory effects of Streptococcus sanguinis extracellular membrane vesicles protect oral gingival epithelial cells from periodontal pathobiont damage

链球菌胞外膜囊泡的免疫刺激作用可保护口腔龈上皮细胞免受牙周致病菌的损害。

Helliwell, Emily; Rauch, Isabella; Nice, Tim; Merritt, Justin; Kreth, Jens

Epithelial Pyroptosis in Host Defense

宿主防御中的上皮细胞焦亡

Churchill, Madeline J; Mitchell, Patrick S; Rauch, Isabella

Innate immune sensing by epithelial barriers

上皮屏障的先天免疫感知

Constant, David A; Nice, Timothy J; Rauch, Isabella

Transcriptional profiling identifies caspase-1 as a T cell-intrinsic regulator of Th17 differentiation.

转录组分析表明 caspase-1 是 T 细胞内在的 Th17 分化调节因子

Gao Yajing, Deason Krystin, Jain Aakanksha, Irizarry-Caro Ricardo A, Dozmorov Igor, Coughlin Laura A, Rauch Isabella, Evers Bret M, Koh Andrew Y, Wakeland Edward K, Pasare Chandrashekhar

Intestinal restriction of Salmonella Typhimurium requires caspase-1 and caspase-11 epithelial intrinsic inflammasomes

沙门氏菌在肠道中的限制需要 caspase-1 和 caspase-11 上皮固有炎症小体。

Crowley, Shauna M; Han, Xiao; Allaire, Joannie M; Stahl, Martin; Rauch, Isabella; Knodler, Leigh A; Vallance, Bruce A

NAIP-NLRC4 Inflammasomes Coordinate Intestinal Epithelial Cell Expulsion with Eicosanoid and IL-18 Release via Activation of Caspase-1 and -8

NAIP-NLRC4炎症小体通过激活Caspase-1和-8协调肠上皮细胞排出以及类花生酸和IL-18的释放。

Rauch, Isabella; Deets, Katherine A; Ji, Daisy X; von Moltke, Jakob; Tenthorey, Jeannette L; Lee, Angus Y; Philip, Naomi H; Ayres, Janelle S; Brodsky, Igor E; Gronert, Karsten; Vance, Russell E

NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo

NAIP蛋白是胞质内检测特定细菌配体所必需的。

Rauch, Isabella; Tenthorey, Jeannette L; Nichols, Randilea D; Al Moussawi, Khatoun; Kang, James J; Kang, Chulho; Kazmierczak, Barbara I; Vance, Russell E

Intestinal Microbiota Signatures Associated with Inflammation History in Mice Experiencing Recurring Colitis

小鼠复发性结肠炎的炎症史与肠道菌群特征相关

Berry, David; Kuzyk, Orest; Rauch, Isabella; Heider, Susanne; Schwab, Clarissa; Hainzl, Eva; Decker, Thomas; Müller, Mathias; Strobl, Birgit; Schleper, Christa; Urich, Tim; Wagner, Michael; Kenner, Lukas; Loy, Alexander

Intestinal Epithelial Cell Tyrosine Kinase 2 Transduces IL-22 Signals To Protect from Acute Colitis

肠上皮细胞酪氨酸激酶2传递IL-22信号以预防急性结肠炎

Hainzl, Eva; Stockinger, Silvia; Rauch, Isabella; Heider, Susanne; Berry, David; Lassnig, Caroline; Schwab, Clarissa; Rosebrock, Felix; Milinovich, Gabriel; Schlederer, Michaela; Wagner, Michael; Schleper, Christa; Loy, Alexander; Urich, Tim; Kenner, Lukas; Han, Xiaonan; Decker, Thomas; Strobl, Birgit; Müller, Mathias