日期:
2020 年 — 2026 年
2020
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2026
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Corrigendum to High IFN-γ and low SLPI mark severe asthma in mice and humans

关于“高IFN-γ和低SLPI标志着小鼠和人类的严重哮喘”一文的更正

Raundhal, Mahesh; Morse, Christina; Khare, Anupriya; Oriss, Timothy B; Milosevic, Jadranka; Trudeau, John; Huff, Rachael; Pilewski, Joseph; Holguin, Fernando; Kolls, Jay; Wenzel, Sally; Ray, Prabir; Ray, Anuradha

Blockade of IL-22 signaling reverses erythroid dysfunction in stress-induced anemias

阻断 IL-22 信号可逆转应激性贫血中的红细胞功能障碍

Mahesh Raundhal, Shrestha Ghosh, Samuel A Myers, Michael S Cuoco, Meromit Singer, Steven A Carr, Sushrut S Waikar, Joseph V Bonventre, Jerome Ritz, Richard M Stone, David P Steensma, Aviv Regev, Laurie H Glimcher

IRE1α-XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity

IRE1α-XBP1通过调节线粒体活性来控制卵巢癌中的T细胞功能。

Minkyung Song ,Tito A Sandoval ,Chang-Suk Chae ,Sahil Chopra ,Chen Tan ,Melanie R Rutkowski ,Mahesh Raundhal ,Ricardo A Chaurio ,Kyle K Payne ,Csaba Konrad ,Sarah E Bettigole ,Hee Rae Shin ,Michael J P Crowley ,Juan P Cerliani ,Andrew V Kossenkov ,Ievgen Motorykin ,Sheng Zhang ,Giovanni Manfredi ,Dmitriy Zamarin ,Kevin Holcomb ,Paulo C Rodriguez ,Gabriel A Rabinovich ,Jose R Conejo-Garcia ,Laurie H Glimcher ,Juan R Cubillos-Ruiz

The mito-DAMP cardiolipin blocks IL-10 production causing persistent inflammation during bacterial pneumonia

线粒体损伤相关分子模式(mito-DAMP)心磷脂可抑制IL-10的产生,从而导致细菌性肺炎期间的持续性炎症。

Krishnendu Chakraborty ,Mahesh Raundhal ,Bill B Chen ,Christina Morse ,Yulia Y Tyurina ,Anupriya Khare ,Timothy B Oriss ,Rachael Huff ,Janet S Lee ,Claudette M St Croix ,Simon Watkins ,Rama K Mallampalli ,Valerian E Kagan ,Anuradha Ray ,Prabir Ray

Respiratory syncytial virus infection of newborn CX3CR1-deficient mice induces a pathogenic pulmonary innate immune response

呼吸道合胞病毒感染新生CX3CR1缺陷小鼠可诱导致病性肺部固有免疫反应。

Sudipta Das ,Mahesh Raundhal ,Jie Chen ,Timothy B Oriss ,Rachael Huff ,John V Williams ,Anuradha Ray ,Prabir Ray

Severe asthma in humans and mouse model suggests a CXCL10 signature underlies corticosteroid-resistant Th1 bias

人类和小鼠模型中的严重哮喘表明 CXCL10 特征是皮质类固醇抵抗性 Th1 偏差的基础

Marc Gauthier, Krishnendu Chakraborty, Timothy B Oriss, Mahesh Raundhal, Sudipta Das, Jie Chen, Rachael Huff, Ayan Sinha, Merritt Fajt, Prabir Ray, Sally E Wenzel, Anuradha Ray

IRF5 distinguishes severe asthma in humans and drives Th1 phenotype and airway hyperreactivity in mice

IRF5 可区分人类严重哮喘,并驱动小鼠 Th1 表型和气道高反应性

Timothy B Oriss, Mahesh Raundhal, Christina Morse, Rachael E Huff, Sudipta Das, Rachel Hannum, Marc C Gauthier, Kathryn L Scholl, Krishnendu Chakraborty, Seyed M Nouraie, Sally E Wenzel, Prabir Ray, Anuradha Ray

Mitochondrial H2O2 in Lung Antigen-Presenting Cells Blocks NF-κB Activation to Prevent Unwarranted Immune Activation

肺抗原呈递细胞中的线粒体 H2O2 阻断 NF-κB 激活,从而防止不必要的免疫激活

Anupriya Khare, Mahesh Raundhal, Krishnendu Chakraborty, Sudipta Das, Catherine Corey, Christelle K Kamga, Kelly Quesnelle, Claudette St Croix, Simon C Watkins, Christina Morse, Timothy B Oriss, Rachael Huff, Rachel Hannum, Prabir Ray, Sruti Shiva, Anuradha Ray

High IFN-γ and low SLPI mark severe asthma in mice and humans

高 IFN-γ 和低 SLPI 标记小鼠和人类严重哮喘

Mahesh Raundhal, Christina Morse, Anupriya Khare, Timothy B Oriss, Jadranka Milosevic, John Trudeau, Rachael Huff, Joseph Pilewski, Fernando Holguin, Jay Kolls, Sally Wenzel, Prabir Ray, Anuradha Ray

Cutting Edge: Dual Function of PPARγ in CD11c+ Cells Ensures Immune Tolerance in the Airways

前沿研究:PPARγ在CD11c+细胞中的双重功能确保气道免疫耐受

Khare, Anupriya; Chakraborty, Krishnendu; Raundhal, Mahesh; Ray, Prabir; Ray, Anuradha