Targeted genetic and small molecule disruption of N-Ras CaaX cleavage alters its localization and oncogenic potential.
通过靶向基因和小分子手段破坏 N-Ras CaaX 的切割,可以改变其定位和致癌潜力
期刊:Bioorganic Chemistry
影响因子:4.7
doi:10.1016/j.bioorg.2024.107316
Hildebrandt Emily R, Hussain Shaneela A, Sieburg Michelle A, Ravishankar Rajani, Asad Nadeem, Gore Sangram, Ito Takahiro, Hougland James L, Dore Timothy M, Schmidt Walter K