日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Magical moments in protease biology: proteasome autocatalytic activation and PI31-mediated inhibition

蛋白酶生物学中的神奇时刻：蛋白酶体的自催化激活和PI31介导的抑制

期刊:Trends in Biochemical Sciences
影响因子:11
doi:10.1016/j.tibs.2026.02.003
Rajakumar, Tamayanthi; Perez, Erignacio Fermin; Fung, Darlene; Rawson, Shaun; Walsh, Richard M Jr; Hanna, John
发表日期：2026
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Structures of folding intermediates on BAM show diverse substrates fold by a conserved mechanism

BAM 上折叠中间体的结构表明，不同的底物通过保守的机制进行折叠。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2534936123
Thomson, Benjamin D; Marquez, Melissa D; Rawson, Shaun; Dos Santos, Thiago M A; Harrison, Stephen C; Kahne, Daniel
发表日期：2026
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Evidence supporting a catalytic pentad mechanism for the proteasome and other N-terminal nucleophile enzymes.

支持蛋白酶体和其他 N 端亲核酶催化五联体机制的证据

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-58077-x
Fung Darlene, Razi Aida, Pandos Michael, Velez Benjamin, Fermin Perez Erignacio, Adams Lea, Rawson Shaun, Walsh Richard M Jr, Hanna John
免疫/内分泌
发表日期：2025
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Cryo-EM structures of CRAF/MEK1/14-3-3 complexes in autoinhibited and open-monomer states reveal features of RAF regulation.

CRAF/MEK1/14-3-3 复合物在自身抑制和开放单体状态下的冷冻电镜结构揭示了 RAF 调控的特征

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-63227-2
Jang Dong Man, Boxer Kayla, Ha Byung Hak, Tkacik Emre, Levitz Talya, Rawson Shaun, Metivier Rebecca J, Schmoker Anna, Jeon Hyesung, Eck Michael J
信号转导
发表日期：2025
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Structures of folding intermediates on BAM show diverse substrates fold by a uniform mechanism

BAM上折叠中间体的结构表明，不同的底物通过统一的机制进行折叠。

期刊:
影响因子:
doi:10.1101/2025.10.16.682720
Thomson, Benjamin D; Marquez, Melissa D; Rawson, Shaun; Dos Santos, Thiago M A; Harrison, Stephen C; Kahne, Daniel
发表日期：2025
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Antibodies expand the scope of angiotensin receptor pharmacology.

抗体拓展了血管紧张素受体药理学的研究范围

期刊:Nature Chemical Biology
影响因子:13.7
doi:10.1038/s41589-024-01620-6
Skiba Meredith A, Sterling Sarah M, Rawson Shaun, Zhang Shuhao, Xu Huixin, Jiang Haoran, Nemeth Genevieve R, Gilman Morgan S A, Hurley Joseph D, Shen Pengxiang, Staus Dean P, Kim Jihee, McMahon Conor, Lehtinen Maria K, Rockman Howard A, Barth Patrick, Wingler Laura M, Kruse Andrew C
心血管
发表日期：2024
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Mechanism of autocatalytic activation during proteasome assembly.

蛋白酶体组装过程中的自催化激活机制

期刊:Nature Structural & Molecular Biology
影响因子:10.1
doi:10.1038/s41594-024-01262-1
Velez Benjamin, Walsh Richard M Jr, Rawson Shaun, Razi Aida, Adams Lea, Perez Erignacio Fermin, Jiao Fenglong, Blickling Marie, Rajakumar Tamayanthi, Fung Darlene, Huang Lan, Hanna John
免疫/内分泌
发表日期：2024
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Publisher Correction: Cryo-EM structure of a RAS/RAF recruitment complex

出版商更正：RAS/RAF募集复合物的冷冻电镜结构

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-023-41365-9
Park, Eunyoung; Rawson, Shaun; Schmoker, Anna; Kim, Byeong-Won; Oh, Sehee; Song, Kangkang; Jeon, Hyesung; Eck, Michael J
RAS
发表日期：2023
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Structure of the preholoproteasome reveals late steps in proteasome core particle biogenesis

全蛋白酶体前体的结构揭示了蛋白酶体核心颗粒生物合成的后期步骤

期刊:Nature Structural & Molecular Biology
影响因子:10.1
doi:10.1038/s41594-023-01081-w
Walsh, Richard M Jr; Rawson, Shaun; Schnell, Helena M; Velez, Benjamin; Rajakumar, Tamayanthi; Hanna, John
发表日期：2023
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Practices for running a research-oriented shared cryo-EM facility

运行以研究为导向的共享冷冻电镜设施的实践方法

期刊:Frontiers in Molecular Biosciences
影响因子:4
doi:10.3389/fmolb.2022.960940
Walsh, Richard M Jr; Mayer, Megan L; Sun, Christopher H; Rawson, Shaun; Nair, Remya; Sterling, Sarah M; Li, Zongli
发表日期：2022
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