日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Atlas of HIV cis-regulatory elements reveals extensive transcriptional variation across clades, isolates, and within individuals

HIV顺式调控元件图谱揭示了不同分支、分离株以及个体内部广泛的转录变异。

Engin, Berkay; ElSadec, Mohamed Y; Finkelberg, Joseph A; Taslim, Tommy H; Bryant, Daniel L; Soto-Ugaldi, Luis; Kales, Susan; Ho, Ching-Huang; Dashtiahangar, Maryam; Muñoz-Esquivel, George; Morara, Elvis; Purinton, Jacob; D'Elia, Benedetta; Castro, Rodrigo; Chandok, Harshpreet; Paz, Matias A; Siggers, Trevor; Ray, John P; Henderson, Andrew J; Tewhey, Ryan; Fuxman Bass, Juan I

A haplotype-resolved view of human gene regulation.

基于单倍型解析的人类基因调控观点

Vollger Mitchell R, Swanson Elliott G, Neph Shane J, Ranchalis Jane, Munson Katherine M, Ho Ching-Huang, Cheng Y H Hank, Sedeño-Cortés Adriana E, Fondrie William E, Bohaczuk Stephanie C, Dippel Maxwell A, Mao Yizi, Parmalee Nancy L, Mallory Benjamin J, Harvey William T, Kwon Younjun, Garcia Gage H, Hoekzema Kendra, Meyer Jeffrey G, Cicek Mine, Eichler Evan E, Noble William S, Witten Daniela M, Bennett James T, Ray John P, Stergachis Andrew B

Expanding the DNA Motif Lexicon of the Transcriptional Regulatory Code.

扩展转录调控密码的DNA基序词汇

Fan Jingyu, Chaudhri Virendra K, Bisht Deepa, Pease Nicholas A, Hall David Reed, Gerges Peter, Yi Vivian Fang, Kales Susan, Ho Ching-Huang, Das Jishnu, Ray John P, Tewhey Ryan, Meyer Clifford A, Sahni Nidhi, Singh Harinder

Linking candidate causal autoimmune variants to T cell networks using genetic and epigenetic screens in primary human T cells

利用原代人T细胞中的遗传和表观遗传筛选,将候选致病性自身免疫变异与T细胞网络联系起来

Ho, Ching-Huang; Dippel, Maxwell A; McQuade, Meghan S; Mishra, Arpit; Pribitzer, Stephan; Nguyen, LeAnn P; Hardy, Samantha; Chandok, Harshpreet; Chardon, Florence; McDiarmid, Troy A; DeBerg, Hannah A; Buckner, Jane H; Shendure, Jay; de Boer, Carl G; Guo, Michael H; Tewhey, Ryan; Ray, John P

Global discovery of lupus genetic risk variant allelic enhancer activity

全球范围内发现狼疮遗传风险变异等位基因增强子活性

Lu, Xiaoming; Chen, Xiaoting; Forney, Carmy; Donmez, Omer; Miller, Daniel; Parameswaran, Sreeja; Hong, Ted; Huang, Yongbo; Pujato, Mario; Cazares, Tareian; Miraldi, Emily R; Ray, John P; de Boer, Carl G; Harley, John B; Weirauch, Matthew T; Kottyan, Leah C

MAUDE: inferring expression changes in sorting-based CRISPR screens

MAUDE:基于分选的 CRISPR 筛选中表达变化的推断

de Boer, Carl G; Ray, John P; Hacohen, Nir; Regev, Aviv

PTENtiating autoimmunity through Treg cell deregulation

通过 Treg 细胞失调引发自身免疫

Ray, John P; Craft, Joe

The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells

白细胞介素-2-mTORc1激酶轴决定了T辅助细胞1和滤泡B辅助T细胞的信号传导、分化和代谢。

Ray, John P; Staron, Matthew M; Shyer, Justin A; Ho, Ping-Chih; Marshall, Heather D; Gray, Simon M; Laidlaw, Brian J; Araki, Koichi; Ahmed, Rafi; Kaech, Susan M; Craft, Joe

Impact of autoimmune risk alleles on the immune system

自身免疫风险等位基因对免疫系统的影响

Ray, John P; Hacohen, Nir

The transforming growth factor beta signaling pathway is critical for the formation of CD4 T follicular helper cells and isotype-switched antibody responses in the lung mucosa

转化生长因子β信号通路对于肺黏膜中CD4 T滤泡辅助细胞的形成和同型转换抗体反应至关重要。

Marshall, Heather D; Ray, John P; Laidlaw, Brian J; Zhang, Nianzhi; Gawande, Dipika; Staron, Matthew M; Craft, Joe; Kaech, Susan M