日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Synthetic auxotrophy reveals metabolic regulation of plasma cell generation, affinity maturation, and cytokine receptor signaling

合成营养缺陷型揭示了浆细胞生成、亲和力成熟和细胞因子受体信号传导的代谢调控

Cho, Sung Hoon; Brookens, Shawna K; Raybuck, Ariel L; Meyer, Kaylor; Paik, Yeeun C; Hamilton, Jennie; Li, Jingxin; Kalecky, Karel; Park, Chloe; Hicks, Sakeenah L; Karijolich, John; Bottiglieri, Teodoro H; Rathmell, Jeffrey C; Mogilenko, Denis; Scharer, Chris D; Boothby, Mark R

The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness.

B 细胞中的营养感应 Rag-GTPase 复合物通过 TFEB/TFE3 依赖的线粒体适应性来控制体液免疫

Zhu Xingxing, Wu Yue, Li Yanfeng, Zhou Xian, Watzlawik Jens O, Chen Yin Maggie, Raybuck Ariel L, Billadeau Daniel D, Shapiro Virginia Smith, Springer Wolfdieter, Sun Jie, Boothby Mark R, Zeng Hu

Supplying the trip to antibody production-nutrients, signaling, and the programming of cellular metabolism in the mature B lineage

为抗体生成提供营养、信号传导和成熟 B 细胞谱系细胞代谢的程序化

Boothby, Mark R; Brookens, Shawna K; Raybuck, Ariel L; Cho, Sung Hoon

Hypoxia-inducible factors in CD4(+) T cells promote metabolism, switch cytokine secretion, and T cell help in humoral immunity

CD4(+) T细胞中的缺氧诱导因子促进代谢、改变细胞因子分泌,并辅助T细胞参与体液免疫。

Cho, Sung Hoon; Raybuck, Ariel L; Blagih, Julianna; Kemboi, Edna; Haase, Volker H; Jones, Russell G; Boothby, Mark R

B Cell-Intrinsic mTORC1 Promotes Germinal Center-Defining Transcription Factor Gene Expression, Somatic Hypermutation, and Memory B Cell Generation in Humoral Immunity

B细胞内在的mTORC1促进生发中心定义转录因子基因表达、体细胞高频突变和体液免疫中的记忆B细胞生成

Raybuck, Ariel L; Cho, Sung Hoon; Li, Jingxin; Rogers, Meredith C; Lee, Keunwook; Williams, Christopher L; Shlomchik, Mark; Thomas, James W; Chen, Jin; Williams, John V; Boothby, Mark R