The mTOR kinase inhibitors, CC214-1 and CC214-2, preferentially block the growth of EGFRvIII-activated glioblastomas.
mTOR 激酶抑制剂 CC214-1 和 CC214-2 优先阻断 EGFRvIII 激活的胶质母细胞瘤的生长
期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-13-0527
Gini Beatrice, Zanca Ciro, Guo Deliang, Matsutani Tomoo, Masui Kenta, Ikegami Shiro, Yang Huijun, Nathanson David, Villa Genaro R, Shackelford David, Zhu Shaojun, Tanaka Kazuhiro, Babic Ivan, Akhavan David, Lin Kelly, Assuncao Alvaro, Gu Yuchao, Bonetti Bruno, Mortensen Deborah S, Xu Shuichan, Raymon Heather K, Cavenee Webster K, Furnari Frank B, James C David, Kroemer Guido, Heath James R, Hege Kristen, Chopra Rajesh, Cloughesy Timothy F, Mischel Paul S
