日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks

初始T细胞活化过程中,CD27-TRAF2-SHP-1轴信号通路促进记忆相关基因调控网络的形成。

Carla A Jaeger-Ruckstuhl ,Yun Lo ,Elena Fulton ,Olivia G Waltner ,Tamer B Shabaneh ,Sylvain Simon ,Pranav V Muthuraman ,Colin E Correnti ,Oliver J Newsom ,Ian A Engstrom ,Sami B Kanaan ,Shruti S Bhise ,Jobelle M C Peralta ,Raymond Ruff ,Jason P Price ,Sylvia M Stull ,Andrew R Stevens ,Grace Bugos ,Mitchell G Kluesner ,Valentin Voillet ,Vishaka Muhunthan ,Fionnuala Morrish ,James M Olson ,Raphaël Gottardo ,Jay F Sarthy ,Steven Henikoff ,Lucas B Sullivan ,Scott N Furlan ,Stanley R Riddell

Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager

利用计算机模拟胱氨酸致密肽,产生有效的双特异性 T 细胞接合剂

Zachary R Crook, Emily J Girard, Gregory P Sevilla, Mi-Youn Brusniak, Peter B Rupert, Della J Friend, Mesfin M Gewe, Midori Clarke, Ida Lin, Raymond Ruff, Fiona Pakiam, Tinh-Doan Phi, Ashok Bandaranayake, Colin E Correnti, Andrew J Mhyre, Natalie W Nairn, Roland K Strong, James M Olson

A potent peptide-steroid conjugate accumulates in cartilage and reverses arthritis without evidence of systemic corticosteroid exposure

强效肽-类固醇结合物在软骨中积聚并逆转关节炎,无需全身性皮质类固醇暴露的证据

Michelle L Cook Sangar, Emily J Girard, Gene Hopping, Chunfeng Yin, Fiona Pakiam, Mi-Youn Brusniak, Elizabeth Nguyen, Raymond Ruff, Mesfin M Gewe, Kelly Byrnes-Blake, Natalie W Nairn, Dennis M Miller, Christopher Mehlin, Andrew D Strand, Andrew J Mhyre, Colin E Correnti, Roland K Strong, Julian A Si